Double layer co-encapsulation of probiotics and prebiotics by electro-hydrodynamic atomization

Zaeim, Davood; Sarabi-Jamab, Mahboobe; Ghorani, Behrouz; Kadkhodaee, Rassoul

doi:10.1016/j.lwt.2019.04.040

Cited by 68 publications

(31 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore, these biopolymers have great potential for the development of colon-specific delivery systems, that enable localized release of e.g. probiotics [33][34][35][36] . However, as polysaccharides are mostly watersoluble and sensitive to pH variations throughout the GI tract, they need to be modified to prevent an early release before reaching the colon 37,38 .…”

Section: Introductionmentioning

confidence: 99%

Colon-Specific Delivery of Bioactive Agents Using Genipin-Cross-Linked Chitosan Coated Microcontainers

Kamguyan

Torp

Christfort

et al. 2020

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights. Users may download and print one copy of any publication from the public portal for the purpose of private study or research.  You may not further distribute the material or use it for any profit-making activity or commercial gain  You may freely distribute the URL identifying the publication in the public portal If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim.

show abstract

Section: Introductionmentioning

confidence: 99%

Colon-Specific Delivery of Bioactive Agents Using Genipin-Cross-Linked Chitosan Coated Microcontainers

Kamguyan

Torp

Christfort

et al. 2020

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

show abstract

“…Zaeim et al (2017), who likewise assessed electrospray-based microencapsulation of L. plantarum in alginate and consecutive coating with chitosan, showed similar viability reductions of around 2 and 3 log CFU/mL after 1 and 2 h gastric (pH 2.5) exposure, respectively. In another paper from the same authors, chitosan coated alginate microcapsules additionally incorporated with resistant starch, were reported to give a slightly weaker protection for L. plantarum than our resistant starchcontaining microcapsules during the 2 h simulated gastric digestion (Zaeim et al, 2019). No notable alginate gel matrix disintegration was observed for any formulations after the end of the gastric incubation, which can be associated with the fact that alginate exhibits an acid gel attribute at pKa below ~ 3.5 (Nualkaekul et al, 2012;Onsoyen, 1999).…”

Section: Survival Of Free and Microencapsulated Bacteria Exposed To S...mentioning

confidence: 63%

Electrosprayed mucoadhesive alginate-chitosan microcapsules for gastrointestinal delivery of probiotics

Bujna

Kun

et al. 2021

International Journal of Pharmaceutics

View full text Add to dashboard Cite

“…Increased loss in viability was reported and was explained to have occurred because of the acidic gelatin solution and the effect of acetic acid (low pH) on a drastic reduction of cell viability during storage. In a different approach, Zaeim et al [ 183 ] performed double-layer co-encapsulation of probiotics along with inulin (prebiotic) using electrospraying. They reported better encapsulation yield and GI survival rates of 5.9 log 10 CFU/g and 7.2 log 10 CFU/g for L. plantarum and B. lactis , respectively.…”

Section: Techniques Used For Encapsulation Of Probioticsmentioning

confidence: 99%

Targeted Delivery of Probiotics: Perspectives on Research and Commercialization

Yoha

Nida

Dutta

et al. 2021

Probiotics & Antimicro. Prot.

View full text Add to dashboard Cite

Considering the significance of the gut microbiota on human health, there has been ever-growing research and commercial interest in various aspects of probiotic functional foods and drugs. A probiotic food requires cautious consideration in terms of strain selection, appropriate process and storage conditions, cell viability and functionality, and effective delivery at the targeted site. To address these challenges, several technologies have been explored and some of them have been adopted for industrial applicability. Encapsulation of probiotics has been recognized as an effective way to stabilize them in their dried form. By conferring a physical barrier to protect them from adverse conditions, the encapsulation approach renders direct benefits on stability, delivery, and functionality. Various techniques have been explored to encapsulate probiotics, but it is noteworthy that the encapsulation method itself influences surface morphology, viability, and survivability of probiotics. This review focuses on the need to encapsulate probiotics, trends in various encapsulation techniques, current research and challenges in targeted delivery, the market status of encapsulated probiotics, and future directions. Specific focus has been given on various in vitro methods that have been explored to better understand their delivery and performance.

show abstract

Double layer co-encapsulation of probiotics and prebiotics by electro-hydrodynamic atomization

Cited by 68 publications

References 47 publications

Colon-Specific Delivery of Bioactive Agents Using Genipin-Cross-Linked Chitosan Coated Microcontainers

Colon-Specific Delivery of Bioactive Agents Using Genipin-Cross-Linked Chitosan Coated Microcontainers

Electrosprayed mucoadhesive alginate-chitosan microcapsules for gastrointestinal delivery of probiotics

Targeted Delivery of Probiotics: Perspectives on Research and Commercialization

Contact Info

Product

Resources

About