Double Inversion Recovery MR Sequence for the Detection of Subacute Subarachnoid Hemorrhage

Abstract

BACKGROUND AND PURPOSE:The diagnosis of subacute subarachnoid hemorrhage is important because rebleeding may occur with subsequent life-threatening hemorrhage. Our aim was to determine the sensitivity of the 3D double inversion recovery sequence compared with CT, 2D and 3D FLAIR, 2D T2*, and 3D SWI sequences for the detection of subacute SAH.

Wave‐CAIPI ViSTa: highly accelerated whole‐brain direct myelin water imaging with zero‐padding reconstruction

“…The proposed wave‐CAIPI ViSTa sequence uses a DIR preparation with a specific configuration, which is potentially capable of being extended to a highly accelerated general DIR sequence for nulling different signal components with multiple clinical purposes, such as WM signal nulling for detecting MS lesions or subarachnoid hemorrhage, blood signal nulling for black‐blood angiography, and so on. The full Cartesian acquisition of these sequences usually takes approximately 4 minutes at present, and it is promising to be able to complete this within 1 minute or even tens of seconds by incorporating wave‐CAIPI.…”

Subarachnoid hemorrhage in ten questions

“…On the other hand, combining FLAIR with T2*-weighted imaging can achieve a sensitivity of 99% in the first 15 days after the onset of symptoms. More recently, double inversion recovery (DAR) 3D sequences have detected SAH 15 days after the initial symptoms [16].…”

Detection of aneurysmal subarachnoid hemorrhage 3 months after initial bleeding: evaluation of T2* and FLAIR MR sequences at 3 T in comparison with initial non-enhanced CT as a gold standard

“…Many studies have reported a higher sensitivity of MR sequences, including fluid-attenuated inversion recovery (FLAIR) sequence,15–20 T2*-weighted (T2*) sequence,15 21 22 susceptibility-weighted imaging (SWI),19 23 or, more recently, double inversion recovery (DIR) sequence,24 for the detection of SAH at the acute and subacute stages (up to 45 days after the occurrence of SAH). Conversely, although the high sensitivity of T2* to intracerebral hemorrhage up to several months after hemorrhage has been established,25 only a few studies have investigated the potential of such MR sequences for detecting SAH at the chronic stage, a few months after the occurrence of bleeding 26–28.…”