Double‐Blind Comparative Trial With 2 Antiregurgitation Formulae

Abstract

The efficacy of both ARF was demonstrated by the decreased number and volume of regurgitations. ARF-2 was statistically more effective than ARF-1. Comparative trials enable the selection of the best therapeutic option.

Gastroesophageal Reflux

“…Recent data suggest that parental reports during a first consultation may be inaccurate and overestimate the incidence of regurgitation [107], similar to what is well known regarding crying infants or infant colic. The inclusion criterion for a multicenter French study was more than five episodes of regurgitation per day since more than 1 week [107].…”

“…Laparoscopic surgery a limited data on 40 ° supine sleeping position in infants GERD gastroesophageal reflux disease, NERD non-erosive reflux disease was recorded prospectively [107]. These findings question the efficacy of "reassurance and guidance" which in most studies turns around 20 %.…”

“…The inclusion criterion for a multicenter French study was more than five episodes of regurgitation per day since more than 1 week [107]. The study started with a 3-day baseline diary, and only 75 % of the infants said initially to regurgitate more than five times did effectively so when the frequency of regurgitation Phase 1 Parental reassurance, observation, life-style changes, exclude overfeeding Phase 2…”

“…However, there are no data that relate ingested volume to frequency and volume of regurgitation, although it seems logical to hypothesize that feeding of large volumes favors regurgitations since it will increase TLESRs. Reassurance while showing compassion for the impaired quality of life is of importance [1,3,106,107].…”

Dietotherapy of Functional Digestion Disorders in Children of the First Several Months of Life

“…В случаях, когда колики оказываются признаком гастроинтестинальной формы пищевой аллергии, которая в этом возрасте чаще всего обусловлена непереносимостью белков коровье-го молока, ребенок должен получать питание, соответ-ствующее принципам диетотерапии пищевой аллергии (т. е. смеси на основе гидролизатов белков коровьего молока, на основе козьего молока или смеси на основе белков сои) [12]. Для детей с синдромом срыгиваний предназначены специализированные антирефлюксные молочные смеси, в которых в качестве загустителей используют 2 типа полисахаридов: неперевариваемые (камеди, составляющие основу клейковины рожкового дерева) или перевариваемые (рисовый или кукурузный крахмал) [13][14][15].…”