Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage kidney disease

Daly, Conal; Cody, June D; Khan, Izhar; Rabindranath, Kannaiyan S; Vale, Luke; Wallace, S

doi:10.1002/14651858.cd003078.pub2

Cited by 23 publications

(11 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Over these years, two important changes were made in the care of PD patients, namely the use of the disconnect system since 1994 and the use of biocompatible solutions since 2005. Several previous reports have suggested that PD device advancement from a single bag to twin-bag systems has reduced the incidence of touch contamination causing PDassociated peritonitis (2). Our data showed that twin-bag systems have had a favorable effect on the incidence of PD-associated peritonitis, as was also reported by van Esch et al (18).…”

Section: Discussionsupporting

confidence: 86%

“…As previously identified, changing from single-bag to twin-bag systems specifically reduced infection with Staphylococcus sp. (2,18), as well as PD-associated peritonitis, at a global level. Pseudomonas aeruginosa accounted for 13.2% of PD-associated peritonitis episodes between 1995 and 1999 in Hong Kong, and for 5.3% of cases between 2003 and 2006 in Australia (23).…”

Section: Discussionmentioning

confidence: 99%

“…Several preventive strategies have been developed for these complications, focusing on the modalities and technologies applied. For example, PD device advancement from single-bag to twin-bag systems mitigates the impact of touch contamination causing PD-associated peritonitis (2). In addition, the switch to biocompatible PD solutions, characterized by neutral pH and low glucose degradation product (GDP) content, from conventional PD solutions appeared to be protective against peritoneal membrane damage and ultrafiltration failure (3).…”

mentioning

confidence: 99%

See 2 more Smart Citations

33 Years of Peritoneal Dialysis‐Associated Peritonitis: A Single‐Center Study in Japan

et al. 2015

View full text Add to dashboard Cite

Peritoneal dialysis-associated peritonitis (PD-associated peritonitis) could influence the outcome of PD patients, including technique survival. Although the use of the twin-bag system has decreased the incidence of peritonitis, the effects of biocompatible PD solutions are controversial. Additionally, since both infection-causing microorganisms and antimicrobial therapies have changed over time, the duration of treatment of peritonitis (the duration of peritonitis) seems to have changed. The study included 527 patients who received PD between January 1980 and December 2012 at a single center. We divided patients undergoing PD into three groups according to the type of PD system used, namely single-bag and conventional PD solutions (S+C group, N = 145), twin-bag and conventional PD solutions (T+C group, N = 171) and twin-bag and biocompatible PD solutions (T+B group, N = 211), and analyzed PD-associated peritonitis incidences. Incidences of PD-associated peritonitis (times per patient-months) and peritonitis-free time were 1/59.4, 1/70.6 and 1/103.1, and 52, 97, and 100 months for the S+C, T+C and T+B groups, respectively. The duration of peritonitis, has thus, become dramatically shorter in recent years. Streptococcus sp. were associated with shortest and fungi with longest durations of peritonitis. Staphylococcus sp. and Pseudomonas aeruginosa were predominant in the S+C group. The twin-bag system has made a greater contribution to reductions in PD-associated peritonitis than biocompatible PD solutions. Furthermore, changes in microorganisms, antimicrobial therapies, patient education and improved PD system devices have presumably affected the reduction in the duration of peritonitis.

show abstract

Section: Discussionsupporting

confidence: 86%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

33 Years of Peritoneal Dialysis‐Associated Peritonitis: A Single‐Center Study in Japan

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Previous studies identified peritonitis as an independent risk factor for patients and technique survival in PD patients [6,7,13]. The impact of peritonitis changed largely due to the decrease in the peritonitis rate through the use of the double-bag or Y-set [17]. Furthermore, of the number of effective peritonitis treatments increased after the widespread application of the ISPD guidelines [18,19].…”

Section: Discussionmentioning

confidence: 99%

Early Peritonitis is an Independent Risk Factor for Mortality in Elderly Peritoneal Dialysis Patients

Zhi

Jiang

Feng

et al. 2015

Kidney Blood Press Res

View full text Add to dashboard Cite

Background/Aims: The impact of early peritonitis on the outcome of elderly peritoneal dialysis (PD) patients has not been studied. We aimed to research the influence of early peritonitis on patient outcomes in elderly PD patients. Methods: This study involved elderly PD patients (age ≥65) who underwent PD between Jan 1, 2004 and Jul 31, 2013. Patient characteristics were collected in our database. Early peritonitis was defined as peritonitis within 6 months after the initiation of PD. Patient survival and technique were compared among the non-peritonitis, early peritonitis and late peritonitis groups using Cox regression analysis. Results: There were 155 subjects involved in this study. The patients were divided among a non-peritonitis group (n=78), early peritonitis group (n=32) and late peritonitis group (n=45). The organisms causing first peritonitis in the two groups did not differ significantly. After adjustment for age, diabetes, serum albumin and residual renal function, multivariable Cox regression model revealed that compared with the early peritonitis group, both the non-peritonitis group (HR 0.57, RI 0.32-0.99, p=0.046) and the late peritonitis group (HR 0.37, RI 0.16-0.75, p=0.004) exhibited a lower patient mortality rate. Conclusions: Early peritonitis is an independent risk factor for mortality in elderly peritoneal dialysis patients.

show abstract

“…Die Peritonitisrate ist in den letzten Jahren und Jahrzenten kontinuierlich auf zuletzt 0,06-1,66 Ereignisse pro Patientenjahre -in Abhängigkeit vom Zentrum und Land -zurückgegangen [4][5][6][7][8]. Dies wurde durch wichtige technische Entwicklungen wie die Einführung der Doppelkammer-und Y-Systeme sowie den Einsatz von biokompatiblen Lösungen möglich [9][10][11]. Aufgrund dieser Zahlen empfiehlt die International Society for Peritoneal Dialysis (ISPD) in der aktuellen Leitlinie eine Peritonitisrate von unter 0,5 Ereignissen pro Jahr (kleiner als 1 Ereignis pro 24 Monate) [12].…”

unclassified

Update: Infektiöse Komplikationen der Peritonealdialyse

Kitterer

2018

Dialyse aktuell

View full text Add to dashboard Cite

ZusammenfassungInfektiöse Komplikationen stellen weiterhin eine wichtige Komplikation der Peritonealdialyse (PD) dar. Durch technische Entwicklungen der letzten Jahrzehnte sind heutzutage Peritonitisraten möglich, die unter 0,5 Ereignissen pro Jahr (kleiner als 1 Ereignis pro 24 Monate) liegen. Die Vermeidung von Exit-site-Infektionen und die perioperative Single-Shot-Antibiotikagabe stellen weitere Möglichkeiten dar, um Peritonitiden bei PD-Patienten zu vermeiden. Bei der Antibiotikaauswahl müssen lokale Resistenzen sowie koagulasenegative Staphylokokken mit Methicillin-/Oxacillinresistenz beachtet werden. Gramnegative Keime mit Resistenzen gegen Cephalosporine stellen weiterhin erfreulicherweise eine Ausnahme dar. Sollten solche Keime zu einer Peritonitis führen, kommen Carbapeneme intraperitoneal als Alternative in Frage.

show abstract

Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage kidney disease

Abstract: Double bag or Y-set versus standard transfer systems for continuous ambulatory peritoneal dialysis in end-stage kidney disease.

Cited by 23 publications

References 43 publications

33 Years of Peritoneal Dialysis‐Associated Peritonitis: A Single‐Center Study in Japan

33 Years of Peritoneal Dialysis‐Associated Peritonitis: A Single‐Center Study in Japan

Early Peritonitis is an Independent Risk Factor for Mortality in Elderly Peritoneal Dialysis Patients

Update: Infektiöse Komplikationen der Peritonealdialyse

Contact Info

Product

Resources

About