Dotlike Hemosiderin Spots Are Associated With Past Hemorrhagic Strokes in Patients With Lacunar Infarcts

Abstract

Our findings suggest that many deep dotHSs on T2(*)-weighted magnetic resonance imaging may be correlated with deep ICH-lacunar infarction type of SVD recurrence but not lacunar infarction-lacunar infarction type.

Hematoma Size in Deep Intracerebral Hemorrhage and its Correlation with Dot‐Like Hemosiderin Spots on Gradient Echo T2*‐Weighted MRI

“…In several series, CT detected rapid hematoma expansion within 6 hours of onset. 1,3,4 In this study, we measured the maximal diameter of deep ICH on CT after more than 6 (6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24) hours. An important goal of this study was to detect the relationship between dotHSs and the maximal diameter of deep ICH.…”

“…8,10,18,19,26,27 Our previous studies demonstrated that dotHSs may be associated with deep ICH rather than lacunar infarction on the basis of SVD recurrence. 19 Several clinical investigations revealed that dotHSs were correlated with the tendency to bleed after stroke. 14,15 We hypothesized that dotHSs might be associated with a large size of deep ICH.…”

“…16 In addition, our previous studies suggested that a large number of subcortical or deep dotHSs might be associated with occurrence of deep ICH in patients with prior deep ICHs or lacunar infarctions. [17][18][19][20] Thus, dotHS may be markers for the fragility of small vessels and for increased risk of ICH. If dotHS indicates the fragility of small vessels, including perforating arteries or the tendency to bleed, the number of dotHS may be associated with enlargement of deep ICH.…”

The Number of Microbleeds on Gradient T2∗-weighted Magnetic Resonance Image at the Onset of Intracerebral Hemorrhage

“…[4][5][6]8,13 Subcortical MB may arise from amyloid angiopathy, particularly in older patients. 6,7 However, both deep and subcortical MB are associated with the recurrence of small-vessel disease including deep ICH and lacunar infarction. [4][5][6] In addition, the number of subcortical MB is linearly related to the number of deep MB.…”

“…6,7 However, both deep and subcortical MB are associated with the recurrence of small-vessel disease including deep ICH and lacunar infarction. [4][5][6] In addition, the number of subcortical MB is linearly related to the number of deep MB. 4-6 Therefore, we did not differentiate between MB in these locations in this study.…”