Dosimetry Methods

McLaughlin, W.L.; Miller, Arne; Kovács, András; Mehta, K.

doi:10.1007/978-1-4419-0720-2_49

Cited by 10 publications

(6 citation statements)

References 86 publications

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“…Super Fricke solution is recommended when high intensity irradiations are used. As a matter of fact, high-LET radiation can act as a local high intensity irradiations because of the elevated density of ionization and excitation along the ion track 44 , 56 .…”

Section: Methodsmentioning

confidence: 99%

Intermediate LET-like effect in distal part of proton Bragg peak revealed by track-ends imaging during super-Fricke radiolysis

Audouin,

Hofverberg,

Ngono-Ravache

et al. 2023

Sci Rep

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Upstream of the efficiency of proton or carbon ion beams in cancer therapy, and to optimize hadrontherapy results, we analysed the chemistry of Fricke solutions in track-end of 64-MeV protons and 1.14-GeV carbon ions. An original optical setup is designed to determine the primary track-segment yields along the last millimetres of the ion track with a sub-millimetre resolution. The Fe3+-yield falls in the Bragg peak to (4.9 ± 0.4) × 10–7 mol/J and 1.9 × 10–7 mol/J, under protons and carbon ions respectively. Beyond the Bragg peak, a yield recovery is observed over 1 mm for proton beams. It is attributed to the intermediate-LET of protons in this region where their energy decreases and energy distribution becomes broader, in relation with the longitudinal straggling of the beam. Consequently to this LET decrease in the distal part of the Bragg peak, Fe3+-yield increases. For the first time, this signature is highlighted at the chemical level under proton irradiation. Nevertheless, this phenomenon is not identified for carbon ion beams since their straggling is lower. It would need a greater spatial resolution to be observed.

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Section: Methodsmentioning

confidence: 99%

Intermediate LET-like effect in distal part of proton Bragg peak revealed by track-ends imaging during super-Fricke radiolysis

Audouin,

Hofverberg,

Ngono-Ravache

et al. 2023

Sci Rep

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“…We measured the actual power delivered to the solution with calorimetry, which is a standard method in dosimetry used both to measure power rates in various radiation fields and to calibrate standard and routine dosimeters [23] , [51] . The quantification of the temperature rise in calorimetric dosimeters provides a direct measurement of the absorbed power.…”

Section: Methodsmentioning

confidence: 99%

“…Various sonochemical dosimetry methods measure the acoustic activity by detecting hydroxyl radicals; such as the terephthalate dosimeter (which reacts with hydroxyl radicals to generate 2-hydroxyterephthalate) [19] , [22] , the Fricke dosimeter (whereby hydroxyl radicals oxidize Fe 2+ in acid solution) [23] , [24] , [25] and the Weissler dosimeter (where molecular iodine forms from a series of reactions involving iodide and hydroxyl radicals) [15] , [26] , [27] . Rajamma et al [28] recently reviewed the Weissler [29] , Fricke [30] and terephthalic acid [31] methods.…”

Section: Introductionmentioning

confidence: 99%

Electron paramagnetic resonance of sonicated powder suspensions in organic solvents

Laajimi

Mattia

Stein

et al. 2021

Ultrasonics Sonochemistry

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Highlights We sonicated trimethylene and propylene glycol in presence of silica particles. EPR spectroscopy identified and quantified the generated radicals. Radical concentration with 12–26 μm is twice as much as with 0.005–0.015 μm SiO 2 . 0.5% wt. 12–26 μm particles, generates more radicals than 3% wt. particles.

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“…As a matter of fact, high-LET radiation can act as a local high intensity irradiations because of the elevated density of ionization and excitation along the ion track. 44,56 .…”

Section: Super-fricke Solutionmentioning

confidence: 99%

Post-Bragg Peak keV-Secondary Electron Radiolysis Revealed by Track-Ends Imaging of High-Energy Protons.

Audouin

Hofverberg

Ngono-Ravache

et al. 2023

Preprint

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Upstream of the efficiency of proton or carbon ion beams in cancer therapy, and to optimize hadrontherapy results, we analysed the chemistry of Fricke solutions in track-end of 64-MeV protons and 1.14-GeV carbon ions. An original optical setup is designed to determine the primary track-segment yields along the last millimetres of the ion track with a sub-millimetre resolution. The Fe3+-yield falls in the Bragg peak to (4.9±0.4)×10-7 mol/J and 1.9×10-7 mol/J, under protons and carbon ions respectively. Beyond the proton Bragg peak, a yield recovery is observed over 1 mm. It is attributed to the proton beam straggling. Since a dose rate effect is ruled out in this region, keV secondary electrons are hypothesized to produce this intermediate LET effect. They might also provide DNA lesions during proton exposure, potentially at the origin of delayed radio-induced carcinogenesis.

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Dosimetry Methods

Cited by 10 publications

References 86 publications

Intermediate LET-like effect in distal part of proton Bragg peak revealed by track-ends imaging during super-Fricke radiolysis

Intermediate LET-like effect in distal part of proton Bragg peak revealed by track-ends imaging during super-Fricke radiolysis

Electron paramagnetic resonance of sonicated powder suspensions in organic solvents

Post-Bragg Peak keV-Secondary Electron Radiolysis Revealed by Track-Ends Imaging of High-Energy Protons.

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