Dosimetric properties of MAGIC-<i>f</i>polymer gel assessed to Radiotherapy clinical beams

Marques, T; Schwarcke, M; Garrido, C; Baffa, Oswaldo; Nicolucci, Patrícia

doi:10.1088/1742-6596/250/1/012012

Cited by 6 publications

(5 citation statements)

References 6 publications

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“…The slope is approximately half of previous reports performed at lower fields (e.g. (Marques et al 2010)). Figure 2(b) shows D 95% ∆ for the R 2w measurement over the same range.…”

Section: Resultssupporting

confidence: 50%

Polymer gel dosimetry by nuclear Overhauser enhancement (NOE) magnetic resonance imaging

et al. 2018

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The response to radiation of polymer gel dosimeters has previously been measured by magnetic resonance imaging (MRI) in terms of changes in the water transverse relaxation rate (R ) or magnetization transfer (MT) parameters. Here we report a new MRI approach, based on detecting nuclear Overhauser enhancement (NOE) mediated saturation transfer effects, which can also be used to detect radiation and measure dose distributions in MAGIC-f (Methacrylic and Ascorbic Acid and Gelatin Initiated by Copper Solution with formaldehyde) polymer gels. Results show that the NOE effects produced by low powered radiofrequency (RF) irradiation at specific frequencies offset from water may be quantified by appropriate measurements and over a useful range depend linearly on the radiation dose. The NOE effect likely arises from the polymerization of methacrylic acid monomers which become less mobile, facilitating dipolar through-space cross-relaxation and/or relayed magnetization exchange between polymer and water protons. Our study suggests a potential new MRI method for polymer gel dosimetry.

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“…The slope is approximately half of previous reports performed at lower fields (e.g. (Marques et al 2010)). Figure 2(b) shows D 95% ∆ for the R 2w measurement over the same range.…”

Section: Resultssupporting

confidence: 50%

Polymer gel dosimetry by nuclear Overhauser enhancement (NOE) magnetic resonance imaging

et al. 2018

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“…A number of studies have used PENELOPE to evaluate the radiological water equivalence of different solid phantoms for low energy photons (Hill et al 2010, Marques et al 2010. The PENELOPE code has also been used for calculating the dosimetry data from kilovoltage x-ray beams including depth doses, profiles and BSFs as well as radial dose distributions from low energy brachytherapy sources (Assiamah et al 2007, Chica et al 2008, 2009, 2010, Croce et al 2012, Hill et al 2010, Ye et al 2004.…”

Section: Penelopementioning

confidence: 99%

Advances in kilovoltage x-ray beam dosimetry

et al. 2014

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This topical review provides an up-to-date overview of the theoretical and practical aspects of therapeutic kilovoltage x-ray beam dosimetry. Kilovoltage x-ray beams have the property that the maximum dose occurs very close to the surface and thus, they are predominantly used in the treatment of skin cancers but also have applications for the treatment of other cancers. In addition, kilovoltage x-ray beams are used in intra operative units, within animal irradiators and in on-board imagers on linear accelerators and kilovoltage dosimetry is important in these applications as well. This review covers both reference and relative dosimetry of kilovoltage x-ray beams and provides recommendations for clinical measurements based on the literature to date. In particular, practical aspects for the selection of dosimeter and phantom material are reviewed to provide suitable advice for medical physicists. An overview is also presented of dosimeters other than ionization chambers which can be used for both relative and in vivo dosimetry. Finally, issues related to the treatment planning and the use of Monte Carlo codes for solving radiation transport problems in kilovoltage x-ray beams are presented.

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“…Note that the MAGIC-f gel fusion point doubles if 1% of formaldehyde is used [28,33]. After 2008, the MAGIC-f gel with the atomic and chemical composition shown in Figure 3 was proposed and used by most of the studies, including that by T. Marques et al [34]. In the atomic composition (w/w), H (10.33%), O (62.68%), C (23.52%), N (2.52%), and others (0.81%) are used.…”

Section: Magic-gel Composition and Fabricationmentioning

confidence: 99%

“…Moreover, the research on dose rate dependency reveals that the MAGICf gel shows no major variations of responses in different clinical dose rates which vary from 0.44 to 10 Gy/min, i.e., lower than 0.7% when X-rays are considered for evaluation and lower than 1.9% when all high-and low-energy beams (X-ray, γ-rays, photons, etc.) are produced from different accelerators [34]. Alva et al showed the effectiveness of MAGIC-f gel by using small fields in the dosimetric calculation in conformal radiation therapy; this cancer treatment shapes the radiation beam to tally the tumor shape; the effectiveness of MAGIC-f gel is predicted by Monte Carlo simulation, using PENELOPE, and experimentally by irradiating a MAGIC-f gel in phantom of 12 cm diameter and 18 cm height with 9 fields of 6 MV photon beam, each one of 1 × 1 cm2 with a total dose of 16 Gy, and reading the result via MRI [86].…”

Section: Application Of Magic-f Gelmentioning

confidence: 99%

Development and Application of MAGIC-f Gel in Cancer Research and Medical Imaging

2021

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Much of the complex medical physics work requires radiation dose delivery, which requires dosimeters to accurately measure complex three-dimensional dose distribution with good spatial resolution. MAGIC-f polymer gel is one of the emerging new dosimeters widely used in medical physics research. The purpose of this study was to present an overview of polymer gel dosimetry, using MAGIC-f gel, including its composition, manufacture, imaging, calibration, and application to medical physics research. In this review, the history of polymer gel development is presented, along with the applications so far. Moreover, the most important experiments/applications of MAGIC-f polymer gel are discussed to illustrate the behavior of gel on different conditions of irradiation, imaging, and manufacturing techniques. Finally, various future works are suggested based on the past and present works on MAGIC-f gel and polymer gel in general, with the hope that these bits of knowledge can provide important clues for future research on MAGIC-f gel as a dosimeter.

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Dosimetric properties of MAGIC-fpolymer gel assessed to Radiotherapy clinical beams

Cited by 6 publications

References 6 publications

Polymer gel dosimetry by nuclear Overhauser enhancement (NOE) magnetic resonance imaging

Polymer gel dosimetry by nuclear Overhauser enhancement (NOE) magnetic resonance imaging

Advances in kilovoltage x-ray beam dosimetry

Development and Application of MAGIC-f Gel in Cancer Research and Medical Imaging

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