Dosimetric plan evaluation of hypofractionated 3-dimensional conformal radiotherapy (3DCRT) and 2-dimensional (2D) simulator planning in whole breast irradiation after breast conserving surgery
Abstract:Background: Pathologic complete response (pCR) is known to be a predictive marker for favorable outcome after neoadjuvant treatment in HER2 positive (þ) breast cancer. Our aim was to investigate the association between hormone receptor (HR) or tumorinfiltrating lymphocytes (TILs) and pCR in HER2 (þ) breast cancer treated with dual anti-HER2 therapy. Methods: Ninety-four patients with HER2 (þ) breast cancer who received neoadjuvant treatment with docetaxel, carboplatin, trastuzumab and pertuzumab (TCHP) were in… Show more
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