Dosimetric consequences of tumor mobility in radiotherapy of stage I non-small cell lung cancer – an analysis of data generated using ‘slow’ CT scans

Exceptionally high incidence of symptomatic grade 2–5 radiation pneumonitis after stereotactic radiation therapy for lung tumors

“…The target volume corresponded to the internal target volume (ITV) in Japan Clinical Oncology Group (JCOG) 0403 phase II protocol [12]. The CT images already included the internal motion because long scan time (four seconds) CT under free breathing (what is called, "slow" CT scan) was used [13,14]. Spicula formation and pleural indentation were included within the ITV.…”

Stereotactic Body Radiotherapy for Small Lung Tumors in the University of Tokyo Hospital

“…The CT images already included the internal motion because long scan time (four seconds) CT under free breathing (what is called, “slow” CT scan) was used [21, 22]. …”

Small Lung Tumors: Long-Scan-Time CT for Planning of Hypofractionated Stereotactic Radiation Therapy—Initial Findings

“…Lagerwaard et al (12) and van Sörnsen de Koste et al (13), on the basis of two helical CT scans and three "slow" CT scans, reported that planning target volumes derived by using slow CT consistently produced superior target coverage than did those from thin-section CT. On the other hand, attempts have been made at some institutions to avoid the influence of respiratory motion during radiation therapy by using active breathing control (14), breath holding (15), and real-time tumor tracking during radiation therapy (16). In some cases, these methods probably are effective for reducing the volume to be irradiated.…”