Dosimetric Comparison of Superflab and Specially Prepared Bolus Materials Used in Radiotherapy Practice

Aras, Serhat; Tanzer, İhsan Oğuz; İkizceli, Türkan

doi:10.5152/ejbh.2020.5041

Cited by 16 publications

(6 citation statements)

References 14 publications

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“…We found that the customized helmet bolus was more effective than previous studies using conventional flat bolus and 3D-printed bolus. 26 – 28 Notably, there was a deviation in dose distribution, indicating a 64%-111.2% difference. The thickness of the scalp blouse may vary depending on the location, which could be a cause for concern as it covers the scalp with a thermoplastic mask.…”

Section: Discussionmentioning

confidence: 99%

Feasibility of Customized Thermoplastic Patient-Specific Helmet Bolus for Scalp Irradiation Using Volumetric-Modulated Arc Therapy Planning

Kim,

Lee,

Hong

2024

Technol Cancer Res Treat

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Introduction: In this study, we sought to develop a thermoplastic patient-specific helmet bolus that could deliver a uniform therapeutic dose to the target and minimize the dose to the normal brain during whole-scalp treatment with a humanoid head phantom. Methods: The bolus material was a commercial thermoplastic used for patient immobilization, and the holes in the netting were filled with melted paraffin. We compared volumetric-modulated arc therapy treatment plans with and without the bolus for quantitative dose distribution analysis. We analyzed the dose distribution in the region of interest to compare dose differences between target and normal organs. For quantitative analysis of treatment dose, OSLD chips were attached at the vertex (VX), posterior occipital (PO), right (RT), and left temporal (LT) locations. Results: The average dose in the clinical target volume was 6553.8 cGy (99.3%) with bolus and 5874 cGy (89%) without bolus, differing by more than 10% from the prescribed dose (6600 cGy) to the scalp target. For the normal brain, it was 3747.8 cGy (56.8%) with bolus and 5484.6 cGy (83.1%) without bolus. These results show that while the dose to the treatment target decreased, the average dose to the normal brain, which is mostly inside the treatment target, increased by more than 25%. With the bolus, the OSLD measured dose was 102.5 ± 1.2% for VX and 101.5 ± 1.9%, 95.9 ± 1.9%, and 81.8 ± 2.1% for PO, RT, and LT, respectively. In addition, the average dose in the treatment plan was 102%, 101%, 93.6%, and 80.7% for VX, PO, RT, and LT. When no bolus was administered, 59.6 ± 2.4%, 112.6 ± 1.8%, 47.1 ± 1.6%, and 53.1 ± 2.3% were assessed as OSLD doses for VX, PO, RT, and LT, respectively. Conclusion: This study proposed a method to fabricate patient-specific boluses that are highly reproducible, accessible, and easy to fabricate for radiotherapy to the entire scalp and can effectively spare normal tissue while delivering sufficient surface dose.

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Section: Discussionmentioning

confidence: 99%

Feasibility of Customized Thermoplastic Patient-Specific Helmet Bolus for Scalp Irradiation Using Volumetric-Modulated Arc Therapy Planning

Kim,

Lee,

Hong

2024

Technol Cancer Res Treat

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“…Transmission penumbra arises as a result of the beam coming from the edges of blocks or collimators. It can be reduced by ensuring that the geometry of the focalized blocks accommodate for beam divergence [31].…”

Section: Penumbramentioning

confidence: 99%

Treatment Planning System in Radiotherapy: A Short Review

Ting,

Ali Rizal,

Othman

2023

EmAIT

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Treatment planning is the core in radiotherapy. The present study aimed to explore the relationship between treatment planning system and radiotherapy. Some of the important steps in radiation treatment planning system have been discussed in this paper such as patient positioning, contouring, and simulation of pre-treatment. Detailed information has been acquired by the author associated with dose calculations in different conditions,techniques used in beam modification. Since ionising radiation creates ions in the cells of the tissues where it travels through, hence it has the capability to treat cancercells. By taking away electrons from atoms and molecules, ions are created. It can therefore either eliminate the genes or inhibit their growth. The molecular processes leading to tissue damage illustrate that ionizing radiation not only globally affects biomolecules but also selectively alters various biomolecules in response to chemotherapy. Linear accelerator is abbreviated as LINAC. It produces high energy electron or X-ray beams using electricity. Although there are many applications for thesebeams, cancer treatment is one of them.

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“…Despite the availability of commercial bolus, there are still some problems with bolus during radiotherapy. Most commercial boluses are in a flaky structure that does not form adequate contact with the irregular surface of patients’ skin, such as the ear, nose, and scalp, resulting in air gaps between the bolus and the irregular skin[ 5 ]. The resulting air gap is very harmful to obtaining the expected distribution of radiation dose at planning target volume (PTV) for achieving a desired therapeutic outcome[ 6 ].…”

Section: Introductionmentioning

confidence: 99%

3D Printing Polymer-based Bolus Used for Radiotherapy

Lü

Song

Yao

et al. 2024

IJB

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Bolus is a kind of auxiliary device used in radiotherapy for the treatment of superficial lesions such as skin cancer. It is commonly used to increase skin dose and overcome the skin-sparing effect. Despite the availability of various commercial boluses, there is currently no bolus that can form full contact with irregular surface of patients’ skin, and incomplete contact would result in air gaps. The resulting air gaps can reduce the surface radiation dose, leading to a discrepancy between the delivered dose and planned dose. To avoid this limitation, the customized bolus processed by three-dimensional (3D) printing holds tremendous potential for making radiotherapy more efficient than ever before. This review mainly summarized the recent development of polymers used for processing bolus, 3D printing technologies suitable for polymers, and customization of 3D printing bolus. An ideal material for customizing bolus should not only have the feature of 3D printability for customization, but also possess radiotherapy adjuvant performance as well as other multiple compound properties, including tissue equivalence, biocompatibility, antibacterial activity, and antiphlogosis.

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Dosimetric Comparison of Superflab and Specially Prepared Bolus Materials Used in Radiotherapy Practice

Cited by 16 publications

References 14 publications

Feasibility of Customized Thermoplastic Patient-Specific Helmet Bolus for Scalp Irradiation Using Volumetric-Modulated Arc Therapy Planning

Feasibility of Customized Thermoplastic Patient-Specific Helmet Bolus for Scalp Irradiation Using Volumetric-Modulated Arc Therapy Planning

Treatment Planning System in Radiotherapy: A Short Review

3D Printing Polymer-based Bolus Used for Radiotherapy

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