Dosimetric characterization of a synthetic single crystal diamond detector in clinical radiation therapy small photon beams

Ciancaglioni, I.; Marinelli, M.; Milani, E.; Prestopino, G.; Verona, C.; Verona-Rinati, G.; Consorti, R.; Petrucci, A.; Notaristefani, F. De

doi:10.1118/1.4729739

Cited by 93 publications

(136 citation statements)

References 40 publications

(58 reference statements)

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“…In order to check device symmetry, measurements were performed at À 301, À 501, and À 901 as well. The observed angular dependence is in agreement with the results previously reported for a similar SCDD in a clinical photon beam [20].…”

Section: Angular Dependencesupporting

confidence: 82%

“…It is worth to point out that the obtained results related to the pre-irradiation, linearity with dose and dose rate dependence measurements with the tested SCDD are fully consistent with the ones previously reported for similar SCDDs tested in clinical photon and electron beams [20,21], indicating that device performance is not dependent on radiation quality. Fig.…”

Section: Pre-irradiation Procedure Dose and Dose Rate Dependencesupporting

confidence: 75%

“…The synthetic SCDD studied in the present work was based on a similar design of a SCDD investigated in a previous paper [20]. Details on device technology, detection mechanism, encapsulation technique and geometrical specifications can be found elsewhere [20,26].…”

Section: Detectors and Measurement Setupmentioning

confidence: 99%

“…Details on device technology, detection mechanism, encapsulation technique and geometrical specifications can be found elsewhere [20,26]. Briefly, the device acts as a Schottky barrier photodiode and was operated in photovoltaic mode, i.e.…”

Section: Detectors and Measurement Setupmentioning

confidence: 99%

“…Novel synthetic single crystal diamond detectors (SCDDs) grown by chemical vapor deposition (CVD) technique at the University of Rome "Tor Vergata" and designed as Schottky photodiodes have been successfully tested for radiotherapy dosimetry applications, in standard and small photon and electron beams [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

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Dosimetric characterization of a synthetic single crystal diamond detector in a clinical 62 MeV ocular therapy proton beam

Marinelli¹,

Pompili²,

Prestopino³

et al. 2014

Nuclear Instruments and Methods in Physics Research Section A:

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a b s t r a c tA synthetic single crystal diamond based Schottky photodiode was tested at INFN-LNS on the proton beam line (62 MeV) dedicated to the radiation treatment of ocular disease. The diamond detector response was studied in terms of pre-irradiation dose, linearity with dose and dose rate, and angular dependence. Depth dose curves were measured for the 62 MeV pristine proton beam and for three unmodulated range-shifted proton beams; furthermore, the spread-out Bragg peak was measured for a modulated therapeutic proton beam. Beam parameters, recommended by the ICRU report 78, were evaluated to analyze depth-dose curves from diamond detector. Measured dose distributions were compared with the corresponding dose distributions acquired with reference plane-parallel ionization chambers. Field size dependence of the output factor (dose per monitor unit) in a therapeutic modulated proton beam was measured with the diamond detector over the range of ocular proton therapy collimator diameters (5-30 mm). Output factors measured with the diamond detector were compared to the ones by a Markus ionization chamber, a Scanditronix Hi-p Si stereotactic diode and a radiochromic EBT2 film. Signal stability within 0.5% was demonstrated for the diamond detector with no need of any pre-irradiation dose. Dose and dose rate dependence of the diamond response was measured: deviations from linearity resulted to be within 70.5% over the investigated ranges of 0.5-40.0 Gy and 0.3-30.0 Gy/min respectively. Output factors from diamond detector measured with the smallest collimator (5 mm in diameter) showed a maximum deviation of about 3% with respect to the high resolution radiochromic EBT2 film. Depth-dose curves measured by diamond for unmodulated and modulated beams were in good agreement with those from the reference plane-parallel Markus chamber, with relative differences lower than 7 1% in peak-to-plateau ratios, well within experimental uncertainties. A 2.5% variation in diamond detector response was observed in angular dependence measurements carried-out by varying the proton beam incidence angle in the polar direction. The dosimetric characterization of the tested synthetic single crystal diamond detector clearly indicates its suitability for relative dosimetry in ocular therapy proton beams, with no need of any correction factors accounting for dose rate and linear energy transfer dependence.

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Section: Angular Dependencesupporting

confidence: 82%

Section: Pre-irradiation Procedure Dose and Dose Rate Dependencesupporting

confidence: 75%

Section: Detectors and Measurement Setupmentioning

confidence: 99%

Section: Detectors and Measurement Setupmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Dosimetric characterization of a synthetic single crystal diamond detector in a clinical 62 MeV ocular therapy proton beam

Marinelli¹,

Pompili²,

Prestopino³

et al. 2014

Nuclear Instruments and Methods in Physics Research Section A:

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Accuracy and reliability of a commercial treatment planning system in nontarget regions in modern prostate radiotherapy

Danckaert

Ost

Wagter

2023

J Applied Clin Med Phys

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Background:The currently available treatment planning systems (TPSs) are neither designed nor intended for accurate dose calculations in nontarget regions. The aim of this work is to quantify the accuracy and reliability of nontarget doses calculated by a commercially available TPS. Methods: Nontarget doses calculated by the collapsed cone (CC) (v5.2) algorithm implemented in the RayStation (v6) TPS were compared to measured values. Different scenarios were investigated, from simple static fields to intensity modulated radiotherapy (IMRT) and volumetric modulated arc therapy (VMAT) treatment plans. Deviations and confidence limits (CLs) were calculated between results of calculations and measurements-applying both local (δ) and global (Δ) normalization-for various points of interest (POIs). Results were based on a single-institution experience for one clinical test case (prostate) and evaluated against internationally accepted criteria. Results: Overall, the TPS underestimated the nontarget dose by an average of −17.7% ± 25.3% for IMRT. Quantitatively similar results were obtained for VMAT (−17.6% ± 21.2%). POIs receiving < 5% of the prescription dose were significantly underestimated by the TPS (p-value < 0.05 for both IMRT and VMAT). Dose calculation accuracy was also determined by the contribution of secondary radiation, with measured doses for out-of -field POIs being significantly different from calculated values (p-value < 0.01 for both IMRT and VMAT). Although the CL δ in nontarget regions failed the proposed tolerance criteria (40%) for both IMRT (68.8%) and VMAT (52.6%), the CL Δ was within the tolerance limit (4%) for both treatment techniques (1.9% for IMRT and 1.3% for VMAT). No action levels (7%) were exceeded. Conclusions: Based on the currently available benchmarks our TPS is considered acceptable for clinical use, although the dose in some POIs was poorly predicted by the CC algorithm. Some areas were pointed out where TPSs and linear accelerator control systems can be improved.

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Small field dose measurements using plastic scintillation detector in heterogeneous media

et al. 2017

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Dosimetric characterization of a synthetic single crystal diamond detector in clinical radiation therapy small photon beams

Cited by 93 publications

References 40 publications

Dosimetric characterization of a synthetic single crystal diamond detector in a clinical 62 MeV ocular therapy proton beam

Dosimetric characterization of a synthetic single crystal diamond detector in a clinical 62 MeV ocular therapy proton beam

Accuracy and reliability of a commercial treatment planning system in nontarget regions in modern prostate radiotherapy

Small field dose measurements using plastic scintillation detector in heterogeneous media

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