2015
DOI: 10.1016/j.ijrobp.2015.02.015
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Dosimetric Advantages of Midventilation Compared With Internal Target Volume for Radiation Therapy of Pancreatic Cancer

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Cited by 19 publications
(13 citation statements)
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“…Other delineation approaches with improved contrast between tumor and surrounding tissue to define the tumor borders and including the respiration motion should be investigated such as midventilation and particularly the midposition approach. Previous research showed that a midventilation approach results in significant PTV reduction and significant dose reductions to OARs compared to the iGTV approach, although the delineation process had not been investigated yet [6]. …”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Other delineation approaches with improved contrast between tumor and surrounding tissue to define the tumor borders and including the respiration motion should be investigated such as midventilation and particularly the midposition approach. Previous research showed that a midventilation approach results in significant PTV reduction and significant dose reductions to OARs compared to the iGTV approach, although the delineation process had not been investigated yet [6]. …”
Section: Discussionmentioning
confidence: 99%
“…For the remaining uncertainties, such as organ motion and set-up uncertainties, an additional margin is added to form the planning target volume (PTV). Nowadays, a four-dimensional CT (4DCT) scan is increasingly used to account for tumor motion during respiration [1, 2], for example combined with the internal target volume (ITV) [5] or mid-ventilation approach [6]. For pancreatic cancer patients treated at our department, we combine 4DCT with a modified ITV approach.…”
Section: Introductionmentioning
confidence: 99%
“…Also, the tumor motion magnitude during BH varied considerably from one BH to the next and this could result in substantial inter-fractional uncertainties in the tumor position that would also need to be accounted for. It might be better to use a mid-ventilation approach combined with free breathing as this results in target volumes that are significantly smaller compared with the use of an internal target volume [4].…”
Section: Discussionmentioning
confidence: 99%
“…Alternatively, other planning techniques can be used such as mid-ventilation. In mid-ventilation, the tumor is delineated in its mean respiratory position and a safety margin is calculated by regarding the respiratory tumor motion as random motion [4]. Abdominal compression or technically more challenging techniques such as gating or tracking can also be employed to limit or account for tumor motion [5,6].…”
mentioning
confidence: 99%
“…However, several groups have shown that the respiratory motion of pancreatic tumors measured on a single pretreatment 4DCT is not representative for daily tumor motion [2][3][4]. This discrepancy could limit the benefit of all 4DCT-based respiratory motion management techniques, such as using mid-ventilation [5].…”
Section: Introductionmentioning
confidence: 99%