Dose–Response Relationship of Resistance Training on Metabolic Phenotypes, Body Composition and Lipid Profile in Menopausal Women

Abstract

The relationship between volume training of resistance training (RT), body composition and cardiometabolic profile in menopausal women is poorly understand. This study aimed to evaluate the dose–response relationship of RT on lipid profile, body composition and metabolic phenotypes in menopausal women. A total of 31 women were categorized according to different volume of RT. Body composition was evaluated by DEXA and the cardiometabolic risk by metabolic phenotypes and lipid profile. There was a higher frequency of metabolically unhealthy phenotype in women who practiced RT for less than two years and had a weekly frequency lower than three days a week (p > 0.05). Women with more than two years and a higher weekly frequency of RT had lower trunk fat mass than their counterparties (15.33 ± 7.56 versus 10.57 ± 4.87, p = 0.04; 16.31 ± 7.46 versus 10.98 ± 5.49, p = 0.03, respectively). There was an association between HDL-c and time of RT in years. A moderate correlation was identified between variables of body adiposity, time in years and weekly frequency of RT. The present study concludes that more time in years and weekly frequency of RT practice are associated with lower body adiposity in menopausal women, the first also being associated with HDL-c.

Adipocyte Metabolism and Health after the Menopause: The Role of Exercise

“…In a study examining groups of postmenopausal women with similar weight loss, only the group that exercised experienced a favorable shift in body composition with a reduction in the android to gynoid fat mass ratio [ 114 ]. Research has also shown a dose–response effect of exercise on fat loss and metabolic parameters [ 115 , 116 ]. Earnest et al examined how different “doses” of exercise affected metabolism and found, remarkably, that significant improvement seen in waist circumference, fasting glucose, and systolic blood pressure were dose-dependent, once again highlighting the therapeutic effect of exercise, especially among aging women [ 117 ].…”