Dose–Response Relation Between Work Hours and Cardiovascular Disease Risk

Conway, Sadie H.; Pompeii, Lisa; Roberts, Robert E.; Follis, Jack L.; Gimeno, David

doi:10.1097/jom.0000000000000654

Cited by 22 publications

(21 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Studies involving clinical disease have identified associations of long work hours with acute myocardial infarction, hypertension, CHD, stroke, biological functioning related to the development of CVD, disease pathways, and hematologic markers indicating an increased risk of CVD . Specific work hour thresholds have been associated with increased risk of CVD . In a low‐risk, employed population (Whitehall II Study), the addition of data on work hours to the Framingham risk score improved risk prediction of CHD by 4.7% .…”

Section: Discussionmentioning

confidence: 99%

“…[4][5][6][7][8][9][10][11][12][13][14][15][16][26][27][28]34 Specific work hour thresholds have been associated with increased risk of CVD. 28,29 In a low-risk, employed population (Whitehall II Study), the addition of data on work hours to the Framingham risk score improved risk prediction of CHD by 4.7%. 30 In the Atherosclerosis Risk in Communities study, work organization was associated with carotid intima-media thickness.…”

Section: Discussionmentioning

confidence: 99%

“…Systematic reviews and meta‐analyses of studies on long work hours have identified an increased risk of CVD, particularly at 60 or more work hours, and an increased risk of stroke . A retrospective cohort study of the relationship between work hours and CVD found that working more than 45 hours per week for at least 10 years was associated with increased risk of CVD . From the Whitehall II study, Kivimaki et al demonstrated that data on working hours may improve risk prediction of coronary heart disease (CHD) using the Framingham risk score in low‐risk, working populations.…”

Section: Introductionmentioning

confidence: 99%

“…[26][27][28] A retrospective cohort study of the relationship between work hours and CVD found that working more than 45 hours per week for at least 10 years was associated with increased risk of CVD. 29 From the Whitehall II study, Kivimaki et al 30 demonstrated that data on working hours may improve risk prediction of coronary heart disease (CHD) using the Framingham risk score in low-risk, working populations. According to a recent meta-analysis, the evidence that long working hours are a risk factor for CVD suggests a small increased risk associated with CHD (relative risk: 1.12 [95% confidence interval:…”

mentioning

confidence: 99%

See 3 more Smart Citations

Current work hours and coronary artery calcification (CAC): The Multi‐Ethnic Study of Atherosclerosis (MESA)

Allison

Jorgensen

Fekedulegn

et al. 2019

American J Industrial Med

View full text Add to dashboard Cite

Background Long work hours may be associated with adverse outcomes, including cardiovascular disease. We investigated cross‐sectional associations of current work hours with coronary artery calcification (CAC). Methods Participants (n = 3046; 54.6% men) were from the Multi‐Ethnic Study of Atherosclerosis. The number of hours worked in all jobs was obtained by questionnaire and CAC from computed tomography. The probability of a positive CAC score was modeled using log‐binomial regression. Positive scores were modeled using analysis of covariance and linear regression. Results Sixteen percent of the sample worked over 50 hours per week. The overall geometric mean CAC score was 5.2 ± 10.0; 40% had positive scores. In fully‐adjusted models, prevalence ratios were less than 40 hours: 1.00 (confidence interval [CI]: 0.88‐1.12), 40:(ref), 41 to 49:1.13 (CI: 0.99‐1.30), and ≥50:1.07 (CI: 0.94‐1.23) and longer current work hours were not associated with higher mean CAC scores (<40:56.0 [CI: 47.3‐66.3], 40:57.8 [CI: 45.6‐73.3], 41 to 49:59.2 [CI: 45.2‐77.6], ≥50:51.2 [CI: 40.5‐64.8]; P = .686). Conclusions Current work hours were not independently associated with CAC scores.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Current work hours and coronary artery calcification (CAC): The Multi‐Ethnic Study of Atherosclerosis (MESA)

Allison

Jorgensen

Fekedulegn

et al. 2019

American J Industrial Med

View full text Add to dashboard Cite

show abstract

“…Long working hours have also been found to have significant adverse effects on many risk factors of CVD, such as depressive symptoms and sleep deprivation . Previous meta‐analysis studies conducted by European, US, and Australian researchers have demonstrated dose‐response relationships between working hours and the risk of CVD . In Taiwan, Cheng et al found that Taiwanese men who worked over 60 hours per week had a higher risk of CVD compared with those who worked 40‐48 hours per week.…”

Section: Introductionmentioning

confidence: 99%

Policy changes for preventing and recognizing overwork-related cardiovascular diseases in Taiwan: An overview

Chang

Lin

2019

Journal of Occupational Health

View full text Add to dashboard Cite

Objective Overwork‐related cardiovascular and cerebrovascular disease (CVD) has a large impact on workers' rights and labor standards across East Asian countries. This article describes the background and impact of policies regarding overwork‐related CVD in the past decades in Taiwan. Methods We reviewed government policies, guidelines, literature, and news addressing the problems and impact of policy changes to prevent and recognize overwork‐related CVD since the 1990s, and collected data on overwork‐related CVD cases in Taiwan from 2006 to 2017. Results In 2017, overwork‐related CVD accounted for 13% of all cases of occupational diseases, but 79% of all deaths due to occupational diseases. Guidelines for recognizing overwork‐related CVD cases were established in 1991; however, under‐recognition exists in Taiwan due to poor exposure data on working hours and psychological factors and because most medical expenses are covered by the national health insurance system. Amendments on the guidelines, and stricter policies on overwork prevention were enforced following calls from labor unions, nongovernmental organizations, and legislators, but health disparities were introduced when certain industries were exempted from restrictions. Conclusions Long working hours and other work characteristics increase the risk of overwork‐related CVD. By reviewing the changes in policy for preventing overwork and recognizing overwork‐related disease, we identified the need for clearly defined guidance on evaluating overwork‐related CVD, with specific criteria for working hours and other risk factors regarding work characteristics. National policies that lead to better working conditions and prevent overwork‐related diseases must be developed.

show abstract

Association between working hours, work engagement, and work productivity in employees: A cross-sectional study of the Japanese Study of Health, Occupation, and Psychosocial Factors Relates Equity

Okazaki

Nishi

Susukida

et al. 2019

Journal of Occupational Health

View full text Add to dashboard Cite

Objectives The aims of the study were to investigate the association between working hours, work engagement, and work productivity, and to examine if work engagement moderates the influence of working hours on work productivity. Methods We used cross‐sectional data from the Japanese occupational cohort survey, which involved 2093 employees in a manufacturing industry. Working hours were self‐reported by the study participants. Work productivity was assessed with absolute presenteeism based on the scale of the validated Japanese version of World Health Organization Health and Work Performance Questionnaire (WHO‐HPQ). Work engagement was assessed with the Nine‐item Utrecht work Engagement Scale (UWES‐9). Univariate and multivariable regression analyses were conducted to examine the association of working hours and work engagement with work productivity. We also carried out stratified multivariable regression analysis separately for those with high‐work engagement and those with low‐work engagement. Results Working >40 to 50 hours per week and >50 hours per week were significantly positively associated with work productivity in univariate analysis. However, the significant association no longer held after adjusting for work engagement. Work engagement was positively associated with work productivity even after controlling for potential confounders. Working hours were not significantly associated with work productivity among those with high‐work engagement or among those with low‐work engagement. Conclusions Working hours did not have any significant associations with work productivity when taking work engagement into account. Work engagement did not moderate the influence of working hours on work productivity, though it attenuated the relationship between working hours and work productivity.

show abstract

Dose–Response Relation Between Work Hours and Cardiovascular Disease Risk

Cited by 22 publications

References 35 publications

Current work hours and coronary artery calcification (CAC): The Multi‐Ethnic Study of Atherosclerosis (MESA)

Current work hours and coronary artery calcification (CAC): The Multi‐Ethnic Study of Atherosclerosis (MESA)

Policy changes for preventing and recognizing overwork-related cardiovascular diseases in Taiwan: An overview

Association between working hours, work engagement, and work productivity in employees: A cross-sectional study of the Japanese Study of Health, Occupation, and Psychosocial Factors Relates Equity

Contact Info

Product

Resources

About