Dose-Response Association Between Handgrip Strength and Hypertension: A Longitudinal Study of 76,503 European Older Adults

Polo-López, Ana; Calatayud, Joaquín; Núñez-Cortés, Rodrigo; Andersen, Lars Louis; Moya-Ramón, Manuel; López-Bueno, Rubén

doi:10.1016/j.cpcardiol.2023.101813

Cited by 2 publications

(1 citation statement)

References 29 publications

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“…7 Most recently, a longitudinal study from Europe described a dose-dependent inverse relationship between absolute HGS and hypertension and pointed out the minimum and optimal doses of absolute HGS for diminishing hypertension risk were 28 and 54 kg, respectively, in older adults. 25 However, the optimal dose of absolute HGS is too high to reach for the older, and the longitudinal study merely involved participants with an average age of 65 years; whether these results apply to the younger remains to be elucidated. In a word, absolute HGS showed an uncertain relationship with hypertension risk, which hinders drawing the conclusions that absolute HGS improvement is bound to contribute to lowering hypertension prevalence.…”

Section: Discussionmentioning

confidence: 99%

Muscle quality is negatively related to hypertension prevalence in adults: Results from NHANES 2011–2014

Bai,

Zhao,

Shi

et al. 2023

J of Clinical Hypertension

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Resistance training could counter hypertension and improve muscle quality (MQ), but current evidence about the correlation between MQ and hypertension is limited. The authors aimed to explore this correlation using the data of participants aged 20–59 from NHANES 2011–2014 via a cross‐sectional study. The MQ was quantified as handgrip strength (kg)/lean soft tissue mass (kg) of the dominant arm. Weighted multivariate logistic regression models were mainly utilized to investigate the MQ—hypertension association; linear trend tests and subgroup analysis were also conducted. Moreover, the authors employed weighted multivariate linear regression models to uncover the association between blood pressure (BP) and MQ. Four thousand four hundred and sixty‐nine individuals were enrolled, and 1167 were hypertensive. Hypertensive participants had a lower MQ than normotensive participants. In the totally adjusted model, each unit elevation in MQ was related to a 7% reduction in hypertension prevalence (p =.002). There was a decreasing trend in hypertension prevalence and in systolic BP as the MQ increased from the bottom to the top quartile across all three models (p for trend ≤.01), with a 28% difference (OR: 0.72, 95% CI: 0.54, 0.95) in hypertension prevalence and a 1.88 mm Hg (95% CI: −3.56, −0.20) difference in SBP between the top and bottom quartiles in the fully adjusted model. Subgroup analysis further confirmed the MQ—hypertension inverse association. In conclusions, the MQ was negatively associated with hypertension prevalence and systolic BP, which suggests the MQ may be a protective factor for hypertension and need to be improved.

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Section: Discussionmentioning

confidence: 99%