Dose imaging in radiotherapy with an Ar–CF4 filled scintillating GEM

Fetal, S.T.G.; Eijk, C.W.E. van; Fraga, F.A.F.; Haas, J. de; Kreuger, R.; Vuure, T.L. van; Schippers, J.M.

doi:10.1016/s0168-9002(03)02133-8

Cited by 22 publications

(9 citation statements)

References 12 publications

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“…Fig. 15 shows relative photon intensity of different scintillators at the Bragg peak using 138 MeV protons, where the GEM based device shows much better linearity than the currently used plastic scintillators that suffer from severe quenching at high energy density deposits [27].…”

Section: Other Applicationsmentioning

confidence: 99%

Luminescence and imaging with gas electron multipliers

Fraga

Margato

Fetal

et al. 2003

Nuclear Instruments and Methods in Physics Research Section A:

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Although the GEM has been mainly used as a gaseous preamplifier device, it has been shown that using suitable gaseous mixtures the avalanches emit a large number of photons, in the UV, visible and/or NIR bands. This scintillation, readout by CCDs, has been used recently for the development of imaging detectors to be used with X-rays, alpha particles and neutrons. The luminescence process in the GEM and a summary of its applications will be presented. The latest developments, including the operation of the GEMs in photon counting mode, will also be referred. r

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Section: Other Applicationsmentioning

confidence: 99%

Luminescence and imaging with gas electron multipliers

Fraga

Margato

Fetal

et al. 2003

Nuclear Instruments and Methods in Physics Research Section A:

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“…Moreover, one of its most attractive features for practical use is its radiation-hardness against heavy ion beams [11]. These features are also expected to be present in gaseous detectors such as gas electron multipliers (GEMs) [12,13]. Furthermore, in GEM devices, gas scintillation has good proportionality with primary ionization, and the 2-D distributions of gas scintillation can be easily obtained using optical readout [14].The linearity of gaseous detectors can be further improved for high LET ion beams such as a carbon beam [15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

Development and characterization of optical readout well-type glass gas electron multiplier for dose imaging in clinical carbon beams

et al. 2021

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The use of carbon ion beams in cancer therapy (also known as hadron therapy) is steadily growing worldwide; therefore, the demand for more efficient dosimetry systems is also increasing because daily quality assurance (QA) measurements of hadron radiotherapy is one of the most complex and time consuming tasks. The aim of this study is to develop a two-dimensional dosimetry system that offers high spatial resolution, a large field of view, quick data response, and a linear dose-response relationship.We demonstrate the dose imaging performance of a novel digital dose imager using carbon ion beams for hadron therapy. The dose imager is based on a newly-developed gaseous detector, a well-type glass gas electron multiplier. The imager is successfully operated in a hadron therapy facility with clinical intensity beams for radiotherapy. It features a high spatial resolution of less than 1 mm and an almost linear dose-response relationship with no saturation and very low linear-energy-transfer dependence. Experimental results show that the dose imager has the potential to improve dosimetry accuracy for daily QA.

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“…The optically read out TPC end-cups are usually simple, and consist of cascaded parallel-mesh avalanche multipliers, within which the light emission is higher compared to that in wire structures [4]. Although the O-TPC concept is well established, only a few applications have been published: in the fields of dosimetry [8], [9] radiography [10], thermal neutron instrumentation [11], as well as in the experiment for the study of two-proton radioactive decay of the 45 Fe nucleus [12]. In [9]- [11] the authors made use of the GEM (Gas Electron Multiplier [13]) technique.…”

Section: Introductionmentioning

confidence: 99%

“…Although the O-TPC concept is well established, only a few applications have been published: in the fields of dosimetry [8], [9] radiography [10], thermal neutron instrumentation [11], as well as in the experiment for the study of two-proton radioactive decay of the 45 Fe nucleus [12]. In [9]- [11] the authors made use of the GEM (Gas Electron Multiplier [13]) technique.…”

Section: Introductionmentioning

confidence: 99%

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Amplification and scintillation properties of oxygen-rich gas mixtures for optical-TPC applications

Weissman¹,

Gai²,

Breskin³

et al. 2006

J. Inst.

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We studied electron amplification and light emission from avalanches in oxygencontaining gas mixtures. The mixtures investigated in this work included, among others, CO 2 and N 2 O mixed with Triethylamine (TEA) or N 2 . Double-Step Parallel Gap (DSPG) multipliers and THick Gas Electron Multipliers (THGEM) were investigated. High light yields were measured from CO 2 +N 2 and CO 2 +TEA, though with different emission spectra. We observed the characteristic wave-length emission of N 2 and of TEA and used a polymer wave-length shifter to convert TEA UV-light into the visible spectrum. The results of these measurements indicate the applicability of optical recording of ionizing tracks in a TPC target-detector designed to study the cross-sections of the 16 O( γ ¡ , α ) 12 C reaction, a central problem in nuclear astrophysics.

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Dose imaging in radiotherapy with an Ar–CF4 filled scintillating GEM

Cited by 22 publications

References 12 publications

Luminescence and imaging with gas electron multipliers

Luminescence and imaging with gas electron multipliers

Development and characterization of optical readout well-type glass gas electron multiplier for dose imaging in clinical carbon beams

Amplification and scintillation properties of oxygen-rich gas mixtures for optical-TPC applications

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