Abstract:Background: Partial breast irradiation (PBI) harbors the potential for definitive local tumor control. The optimal dose to the target and the maximal tolerated doses (MTD) of the surrounding tissues are unknown. In this cohort planning study, we assess the maximal dose to the target while keeping the dose to the surrounding organs at risk within their tolerance.Patients and Methods: Planning computed tomography scans of 22 patients with a history of pulmonary or cardiac risk factors and left-sided pT1c pN0/pN1… Show more
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