2015
DOI: 10.1007/978-3-319-19387-8_200
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Dose Enhancement in Radiotherapy by Novel Application Of Gadolinium Based MRI Contrast Agent Nanomagnetic Particles in Gel Dosimetry

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Cited by 8 publications
(9 citation statements)
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“…Hence the theoretical dose enhancement should also be negligible. Experimental data agrees with the physical models (Amirrashedi et al, 2015; J. Cho et al, 2016). Smith et al (2015) used alanine dosimetry with dl ‐alanine impregnated with 5 nm GNPs (3% wt) for measurements under X‐ray, electron and proton irradiation.…”
Section: Physical Mechanismssupporting
confidence: 82%
“…Hence the theoretical dose enhancement should also be negligible. Experimental data agrees with the physical models (Amirrashedi et al, 2015; J. Cho et al, 2016). Smith et al (2015) used alanine dosimetry with dl ‐alanine impregnated with 5 nm GNPs (3% wt) for measurements under X‐ray, electron and proton irradiation.…”
Section: Physical Mechanismssupporting
confidence: 82%
“…The dose enhancement ratios are in good agreement with the results of a previous study. 21 These results demonstrate that the presence of GONs increases hydroxyl radical production; moreover, the radiation enhancement effects of GONs on hydroxyl radical production in aqueous solutions induced by X-rays are dependent on dose and concentration. Studies have shown that oxidative stress produced by nanomaterials can be observed in multiple cell types.…”
mentioning
confidence: 72%
“…[18][19][20] The radiosensitization properties of GONs were first investigated by Amirrashedi et al in a gel-filled phantom, in which the maximum dose enhancement of GONs ranged from 15% to 24%. 21 Seo et al found that the GONs enhancement of the production of ROS under photon and proton irradiation was dose-dependent with a factor of 1.94 compared with that of the radiation-only control. Core-inner-valence ionization of GONs can de-excite electrons via potent Gd-Gd interatomic de-excitation processes.…”
Section: Introductionmentioning
confidence: 99%
“…GdNPs have high electron density. Therefore, ionizing radiation contains notes nanoparticles aqueous solution, in addition to the interaction between ionizing radiation and water can cause water molecules ionization and secondary electron emission, the incident particles and secondary electron interaction with Gd will also lead to request for nanoparticles electron emission increases around a few nanometer scale, electronic further solution of released from water molecules 104). Some scholars found that under photon and proton irradiation, the enhancement of ROS produced by GONs was dose-dependent, and the factor was 1.94 compared with radiation control alone.…”
Section: Common Sensitizing Agentmentioning
confidence: 99%