Dose-dependent effect of H2O2 on hairy roots of Scutellaria baicalensis: growth, composition of fatty acids, and flavones

Solov’eva, A. I.; Stepanova, A. Y.; Ivanova, T. V.; Voronkov, A. S.; Panov, Yu. M.

doi:10.1007/s11240-023-02609-0

Cited by 1 publication

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References 65 publications

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“…From this study, we found that except for chlorogenic acid and baicalein, most of the individual phenolic and flavonoid contents were highest in the AM extract, whereas the antioxidant activities were higher in the AE extract. A previous study reported that baicalein is involved in the cell's protection against oxidative damage [35,36]. The highest antioxidant activity in the AE extract might be due to the high baicalein content.…”

Section: Pearson Correlation Analysis Between the Phenolic And Flavon...mentioning

confidence: 91%

Effects of Different Solvents on the Extraction of Phenolic and Flavonoid Compounds, and Antioxidant Activities, in Scutellaria baicalensis Hairy Roots

Lim,

Kim,

Kwon

et al. 2024

Horticulturae

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The hairy roots (HRs) of Scutellaria baicalensis are widely used and consumed worldwide as a medicine, especially in Asian countries, due to their biological and pharmacological activities. The HRs of this plant are rich in secondary metabolites. However, the optimal method and solvents for the extraction of secondary metabolites from S. baicalensis HRs have not been well studied. Therefore, in this study, S. baicalensis HRs were extracted with different solvents, including water (WE), 99.9% pure methanol (PM), 70% aqueous methanol (AM), 99.9% pure ethanol (PE), and 70% aqueous ethanol (AE). The phenolic and flavonoid compounds and various antioxidant activities of each extract were measured. The AE extract (16.85 ± 0.15%) had a higher yield, which led to the highest accumulation of total phenolic content (TPC) and total flavonoid content (TFC), and antioxidant activity. The TPC and TFC were highest in AE (66.03 ± 0.44 mg GAE/g and 40.11 ± 1.31 mg QE/g, respectively), whereas WE, PM, and PE showed lower values in all assays. In addition, the highest antioxidant activities, such as DPPH, ABTS, and SOD-like scavenging activities and reducing power, were achieved in the AE extract compared to the other solvent extracts. Based on these results, the AE extract showed the highest phenolic and flavonoid accumulation and antioxidant activities, highlighting its potential use in the manufacture of useful materials from S. baicalensis HRs and its novel applications.

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Section: Pearson Correlation Analysis Between the Phenolic And Flavon...mentioning

confidence: 91%

Effects of Different Solvents on the Extraction of Phenolic and Flavonoid Compounds, and Antioxidant Activities, in Scutellaria baicalensis Hairy Roots

Lim,

Kim,

Kwon

et al. 2024

Horticulturae

View full text Add to dashboard Cite

show abstract

Dose-dependent effect of H2O2 on hairy roots of Scutellaria baicalensis: growth, composition of fatty acids, and flavones

Cited by 1 publication

References 65 publications

Effects of Different Solvents on the Extraction of Phenolic and Flavonoid Compounds, and Antioxidant Activities, in Scutellaria baicalensis Hairy Roots

Effects of Different Solvents on the Extraction of Phenolic and Flavonoid Compounds, and Antioxidant Activities, in Scutellaria baicalensis Hairy Roots

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