Dose- And Wavelength-Dependence of the Photoinactivation of Sunscreens Due to Solar Simulated Radiation

Schauberger, Günther; Maier, H.; Cabaj, Alexander; Martineigh, B.S.; Brunnhofer, K.; Hönigsmann, Herbert

doi:10.1515/bmte.2003.48.s1.542

Cited by 1 publication

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“…In the present study, the quantity of SEF at each radiation dose was defined and used (as the ratio of cell survival in the presence and absence of MP-EO at each radiation dose). This quantity corresponds to the well-known quantity of Dose Reduction Factor (DRF), which is defined at D50 [28,29].…”

Section: Pbmcs Viabilitymentioning

confidence: 99%

Effects of Ionizing Radiation on Human Peripheral Blood Mononuclear Cells (PBMCs) in the Presence of Mentha-Pulegium Essential Oil: A Study on the Radioprotective Effect

Hamzian

2022

J Biomed Phys Eng

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Background:The Mentha-Pulegium essential oil (MP-EO) contains different antioxidant compounds and reduces the indirect effects of dispersed ionizing radiation on biological systems.Objective: The current study aimed to assess a possible radio-protective effect of MP-EO on peripheral blood mononuclear cells (PBMCs). Material and Methods:In this experimental study, MP-EO was firstly prepared and PBMCs were then irradiated in various groups with doses of 25 and 200 cGy of X-rays in the presence of IC10 of MP-EO. After incubation times of 48h and 72h, the survival, apoptosis, and necrosis percentages of PBMCs were determined by MTT assay and flow cytometry analyses; the radio-protective effect of MP-EO was examined.Results: In the presence of 80 µg/ml (IC10) MP-EO, the mean survival percentage of irradiated PBMCs by radiation doses of 25 and 200 cGy was significantly increased after 48h of incubation compared with the control. At 72h of incubation, the mean survival percentage of irradiated PBMCs was significantly increased only at 25 cGy. The percentage of apoptosis and necrosis of PBMCs was significantly reduced in the presence of the MP-EO at both incubation times and radiation doses; therefore, the highest reduction was at 200 cGy and 48h incubation compared to the control. Conclusion:MP-EO as a natural, non-toxic, and cost-effective compound can exhibit a favorable in-vitro radio-protective effect by increasing the survival and decreasing the percentage of apoptosis and necrosis of irradiated PBMCs.

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Section: Pbmcs Viabilitymentioning

confidence: 99%

Effects of Ionizing Radiation on Human Peripheral Blood Mononuclear Cells (PBMCs) in the Presence of Mentha-Pulegium Essential Oil: A Study on the Radioprotective Effect

Hamzian

2022

J Biomed Phys Eng

View full text Add to dashboard Cite

show abstract

Dose- And Wavelength-Dependence of the Photoinactivation of Sunscreens Due to Solar Simulated Radiation

Cited by 1 publication

References 2 publications

Effects of Ionizing Radiation on Human Peripheral Blood Mononuclear Cells (PBMCs) in the Presence of Mentha-Pulegium Essential Oil: A Study on the Radioprotective Effect

Effects of Ionizing Radiation on Human Peripheral Blood Mononuclear Cells (PBMCs) in the Presence of Mentha-Pulegium Essential Oil: A Study on the Radioprotective Effect

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