Doppler ultrasound investigation of female infertility

Abstract

This study reviewed recent advances in the use of Doppler ultrasonography for the management and prediction of female infertility outcomes of assisted reproductive technology (ART). Color or power Doppler and three-dimensional power Doppler ultrasound can be used to measure vessels near the ovaries, uterus, and endometrium to assess blood flow. Increased blood flow and reduced resistance to the ovaries, uterus, and endometrium are associated with improved pregnancy outcomes, and their measurement has been suggested as a key factor in ART procedural outcomes.Perifollicular vascularity indices can help predict oocyte quality and maturity. Likewise, endometrial and uterine vascularity could be associated with endometrial receptivity and may assist with embryo transfer timing and pregnancy outcome predictions. With the advancement of Doppler ultrasound technology, this highly potent examination will be used more widely in routine clinical settings for the treatment of female infertility.

Associations between the artificial intelligence scoring system and live birth outcomes in preimplantation genetic testing for aneuploidy cycles

“…The backward stepwise selection in the logistic regression model also revealed that impedance to uterine artery blood flow (i.e., the PI level) was a confounder in this dataset. Studies have described the importance of uterine PI levels that were measured using Doppler ultrasound investigations in IVF–ET cycles [ 31 – 34 ]. One study revealed a positive correlation between IVF outcomes and the uterine scoring system for reproduction, which incorporates the PI level, endometrial thickness, endometrial layering, endometrial motion, endometrial blood flow in zone 3, and myometrial blood flow [ 34 ].…”

“…Studies have described the importance of uterine PI levels that were measured using Doppler ultrasound investigations in IVF–ET cycles [ 31 – 34 ]. One study revealed a positive correlation between IVF outcomes and the uterine scoring system for reproduction, which incorporates the PI level, endometrial thickness, endometrial layering, endometrial motion, endometrial blood flow in zone 3, and myometrial blood flow [ 34 ]. Steer et al and Cacciatore et al asserted that PI level > 3.0 on the day of ET was associated with low uterine receptivity, and implantation became unachievable when the PI levels were > 3.3 [ 31 , 32 ].…”

Phosphodiesterases Mediate the Augmentation of Myogenic Constriction by Inhibitory G Protein Signaling and is Negatively Modulated by the Dual Action of RGS2 and 5

“…In the nonpregnant state, UBF serves the crucial role of facilitating endometrial growth and vascularity, as well as contributing to the readying of the endometrium for the implantation of fertilized ova. 52–54 Given that the uterine vasculature is a high resistivity vascular bed in the nonpregnant state, impedance to blood flow to the uterus is determined mostly by vascular resistance, which, in turn, is determined mainly by myogenic tone and the modulatory effects of vasodilatory factors. 9 , 55 , 56 The UA senses and responds to the cyclical stretch from systemic pressure that drives UBF, and this leads to the generation of a 2-component flow velocity Doppler waveform comprising peak systolic and end diastolic velocities, mimicking the cardiac cycle.…”

A comprehensive approach to the treatment of infertility in women with endometrial pathology

“…Васкуляризація ендометрія та матки допомагає прогнозувати результати вагітності. Тому удосконалені допплерівські ультразвукові технології можна використовувати для діагностики жіночого безпліддя маткового походження [28].…”