Doppler ultrasound assessment and serum cancer antigen 125 in the diagnosis of ovarian tumors

Abstract

Sonographic evaluation with predefined specific criteria for the detection of a solid tumor component is an accurate method of preoperative discrimination between benign and malignant ovarian tumors. A serum CA 125 assay may assist in eliminating false-positive results.

Ultrasound for evaluation of adnexal malignancy: From 2D to 3D ultrasound

“…Power Doppler (PD) imaging could depict more color flow features with vascular perfusion superimposed on B‐mode sonography compared with conventional color Doppler 29,30 . This method was applied to differentiate benign from malignant adnexal masses, and the results are shown in Table 4 31–35 . PD imaging increased the specificity of other diagnostic modalities, especially B‐mode sonography 31–34 .…”

“…Several studies have been reported involving the use of contrast agents in the differentiation of benign and malignant adnexal masses 36–41 . The reports employing color Doppler sonography demonstrated a significant difference in the enhancement patterns between benign and malignant adnexal masses, and the potential of sonographic contrast agents to identify the tumor vascularity 33–35 . However, Flesicher et al 39–41 .…”

“…29,30 This method was applied to differentiate benign from malignant adnexal masses, and the results are shown in Table 4. [31][32][33][34][35] PD imaging increased the specificity of other diagnostic modalities, especially B-mode sonography. [31][32][33][34] However, this method was mainly based on subjective assessment of the vessel distribution, required experience, and was highly observer-dependent.…”

“…[31][32][33][34][35] PD imaging increased the specificity of other diagnostic modalities, especially B-mode sonography. [31][32][33][34] However, this method was mainly based on subjective assessment of the vessel distribution, required experience, and was highly observer-dependent. 35 Harret et al 35 objectively evaluated prediction of the malignancy of adnexal masses employing PD imaging using 'the power Doppler index (PDI) determined by quantification of the number of pixels in a defined region of interest according to the formula: number of colored pixels/ (total number of pixels minus the number of pixels in the fluid or avascular areas)', and PDI showed a higher diagnostic value compared to RI measurement in terms of discriminating between benign and malignant adnexal masses.…”

Tumeurs de l'ovaire et CA 125 en 2006

“…Afin d'améliorer ces performances des index de risque de malignité ont été proposés [28][29][30][31][32][33][34][35][36]. Le calcul de ces index associe dans des algorithmes l'état ménopausique, les caractéristiques échographiques et la valeur du CA 125.…”