Doppler ultrasonography helps discriminate between cirrhotic and non-cirrhotic patients with viral B and C hepatitis

Söker, Gökhan; Öztürk, Agah Bahadır; Gülek, Bozkurt; Kuşçu, Ferit; Doğan, Ümit; Çakalǒglu, Yılmaz

doi:10.1016/j.diii.2015.05.014

Cited by 9 publications

(14 citation statements)

References 29 publications

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“…19 The mean values of HARI were higher in the group with hepatic fibrosis ≥ F2 (group F2/F3/F4), identifying the cut-off point of 0.67 for this index, with a sensitivity of 95.5%, a specificity of 87%, and an accuracy of 93.3%, demonstrating the utility of this index for the evaluation of hepatic heel parenchyma. 20 HARI values > 0.77 may identify the development of significant fibrosis and cirrhosis, with a sensitivity of 70% and a specificity of 68%, but there is no association between the range of values of this index and different degrees of fibrosis due to different aetiologies. In viral hepatopathies, this index also differs significantly between fibrosis bands, being demonstrated in the analysis of Doppler hemodynamic variables and FibroScan data in patients with chronic hepatitis C. 14 When analyzing the cut-off point of Doppler indices to discriminate patients with significant fibrosis/cirrhosis in patients with chronic hepatitis B/hepatitis C, sensitivity and specificity were found to be 72.1% and 82.5% for a HARI > 0.70.…”

Section: Discussionmentioning

confidence: 96%

Doppler ultrasonography: A non‐invasive method used to diagnose and follow up patients with chronic hepatitis C

Franco

Vieira

Dias

et al. 2019

J of Gastro and Hepatol

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Background and Aim This study aimed to investigate the association between the findings of Doppler ultrasonography and transient elastography using FibroScan and to determine the cut‐off points, sensitivity, and specificity of resistance indices, and pulsatility of the hepatic vessels to predict significant hepatic fibrosis. Methods This is a transversal, observational, and analytical study that includes 30 patients with chronic hepatitis C who were admitted at a public referral hospital. Transient elastography and ultrasonographic data were collected, and the linear association between these methods was evaluated using the Pearson test. Various Doppler velocimetric indices were compared according to the presence/absence of significant (≥ F2) fibrosis. Results There was a moderate‐strong linear association between the FibroScan data and the Doppler velocimetric indices and splenic index in the hepatic vessels; the mean values of the indices differed between groups with absent/mild (F0/F1) and significant (≥ F2) hepatic fibrosis. There was an association between the monophasic and biphasic wave pattern of the suprahepatic veins and the stratification of hepatic fibrosis estimated by the values of kilopascal in FibroScan. Conclusion Doppler ultrasonography is a non‐invasive method used to evaluate liver fibrosis, and it presents acceptable sensitivity/specificity for the prediction of fibrosis ≥ F2 in patients with chronic hepatitis C.

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Section: Discussionmentioning

confidence: 96%

Doppler ultrasonography: A non‐invasive method used to diagnose and follow up patients with chronic hepatitis C

Franco

Vieira

Dias

et al. 2019

J of Gastro and Hepatol

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“…Birçok araştırmacı kantitatif Doppler parametrelerini kullanarak karaciğer fibrozisini belirlemeye çalışmıştır. Ancak sadece Doppler parametreleri ile karaciğer fibrozis evresini belirlemek mümkün değildir (2). Kronik hepatit-siroz ayırımının non-invaziv olarak yapılabilmesi büyük klinik yarar sağlayacaktır.…”

Section: Discussionunclassified

“…Birçok çalışmada siroz hastalarında HARI değerinin arttığı gösterilmiştir (2,5,10,(13)(14)(15). El-Kabbany ve ark.…”

Section: Discussionunclassified

“…Virüse bağlı hepatitin ana sonucu karaciğer fibrozisine ilerleme ve sirozdur (1,2). Karaciğer fibrozis evresinin doğru tanımlanması, tedavinin planlanmasında ve kronik karaciğer hastalığının takibinde önemlidir (1).…”

Section: Introductionunclassified

“…Doppler US, B mod US bulguları normal olan kronik karaciğer hastalarında dahi karaciğer hemodinamisindeki değişiklikleri belirler ve ayrıca kalitatif ve kantitatif ölçümlere olanak sağlar (7). Birçok araştırmacı farklı Doppler parametreleri kullanarak bu hemodinamik değişiklikleri değerlendirmeye çalışmıştır (2,5,(8)(9)(10). Kronik karaciğer hastalığı ve sirozu ayırmada fibrozis indeksi tanımlanmış ve fibrozis indeksinin siroz hastalarında daha yüksek olduğu bulunmuştur (11).…”

Section: Introductionunclassified

See 2 more Smart Citations

The Value of Fibrosis Index in Discrimination of Chronic Hepatitis and Cirrhosis

Söker¹,

Gülek²,

Öztürk³

et al. 2017

Haseki

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ÖzAmaç: Kronik hepatit ve siroz ayrımında Doppler ultrasonografi (US) ve fibrozis indeksinin değerini araştırmaktır.Yöntemler: Bu çalışmaya 67 hepatit B ve C'si olan ancak siroz gelişmeyen hasta ve 28 siroz hastası katıldı. Tüm hastalara karaciğere yönelik Doppler US yapıldı. Kantitatif Doppler parametreleri elde edildi ve fibrozis indeksi hesaplandı. Sonuçlar istatistiksel olarak karşılaştırıldı ve kronik hepatit ve siroz gruplarını ayırmak için fibrozis indeks eşik değeri elde edildi. Methods: Sixty-seven non-cirrhotic viral hepatitis B and C patients and 28 cirrhotic patients were included in this study. All patients were examined by liver Doppler US. Quantitative Doppler parameters were obtained and fibrosis index was calculated. The results were evaluated statistically and a cut-off value for fibrosis index was obtained to differentiate between chronic hepatitis and cirrhosis groups.

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Doppler ultrasound in the diagnosis of Budd-Chiari syndrome in children after split liver transplantation

Hak¹,

Dabadie²,

Hery³

et al. 2018

Diagnostic and Interventional Imaging

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Doppler ultrasonography helps discriminate between cirrhotic and non-cirrhotic patients with viral B and C hepatitis

Abstract: It is not possible to diagnose cirrhosis with only hemodynamic changes. However, the cutoff values may be helpful in the selection of patients to undergo the procedure of liver biopsy.

Cited by 9 publications

References 29 publications

Doppler ultrasonography: A non‐invasive method used to diagnose and follow up patients with chronic hepatitis C

Doppler ultrasonography: A non‐invasive method used to diagnose and follow up patients with chronic hepatitis C

The Value of Fibrosis Index in Discrimination of Chronic Hepatitis and Cirrhosis

Doppler ultrasound in the diagnosis of Budd-Chiari syndrome in children after split liver transplantation

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