Doppler Ultrasonographic Indices After Renal Transplantation as Renal Function Predictors

Nezami, Nariman; Tarzamni, Mohammad Kazem; Argani, Hassan; Nourifar, M.

doi:10.1016/j.transproceed.2007.11.036

Cited by 25 publications

(16 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Many studies support the use of these indices. 13,[21][22][23] Kahraman and associates showed that and RI > 0.7 and a PI > 1.1 are associated with a decline in allograft function at 1 year compared to 1 month. 22 Similarly, Barba and colleagues found a cutoff point of 0.7 for RI in predicting graft dysfunction.…”

Section: Discussionmentioning

confidence: 99%

“…8,9 However, there are conflicting data regarding the reliability of some indices, such as the resistive and the pulsatility indices in renal transplant recipients by this technique. [9][10][11][12][13] The present study was designed and conducted to evaluate the association between the value of these indices during the first week after transplant and 3-month outcomes in renal transplant recipients.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Relation of Resistive and Pulsatility Indices With Graft Function After Renal Transplant

Ghorbani

Shirazi²,

Sametzadeh³

et al. 2012

Exp Clin Transplant

View full text Add to dashboard Cite

Objectives: There are conflicting data regarding the use of some measured indices by Doppler ultrasound such as the resistive index and the pulsatility index in predicting renal allograft dysfunction. This study sought to evaluate the association of early postoperative Doppler indices and 3-month serum creatinine levels in renal transplant recipients. Materials and Methods: During a 1-year period, all patients who underwent renal transplant at our hospital were recruited into a prospective study. Doppler ultrasound was performed on all patients 6 days and 3 months after the transplant and the resistive index and the pulsatility index were calculated for each patient. Then, the association between these indices and 3-month outcomes of patients were investigated. Results: Thirty-eight patients including 21 men (mean age, 36.6 ± 13.1 y) were evaluated. There was a positive correlation between the resistive index and the pulsatility index at 6 days after transplant and the serum creatinine measured at the same day (P < .001 and r=0.570 for resistive index; P < .001 and r=0.547 for pulsatility index). There was also a positive correlation between the pulsatility index and the resistive index at 6 days after transplant and 3-month serum creatinine level (P = .009 and r=0.420 for resistive index; P = .009 and r=0.417 for pulsatility index). There were negative correlations between the resistive index and the pulsatility index on the sixth day after surgery and creatinine clearance measured at 6 days and 3 months after transplant. Conclusions: This study reveals a strong-to-medium correlation between the resistive index and the pulsatility index, serum creatinine level, measured 6 days after transplant.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Relation of Resistive and Pulsatility Indices With Graft Function After Renal Transplant

Ghorbani

Shirazi²,

Sametzadeh³

et al. 2012

Exp Clin Transplant

View full text Add to dashboard Cite

show abstract

“…It is used for the early diagnosis of transplant kidney vascular thrombosis and renal artery stenosis [1,2,3,4]. Measurement of the vascular resistive index (RI) by Doppler sonography has been proposed as a non-invasive method to evaluate renal allograft dysfunction, but there are conflicting reports about the clinical utility of this technique.…”

Section: Introductionmentioning

confidence: 99%

“…In a prospective study, Radermacher et al [9] demonstrated that an RI of 0.8 or higher measured at least three months after transplantation was associated with poor allograft outcome independently of other established risk factors, though it is not known whether early RI is also related with long-term outcome. Several reports have related RI, measured at different moments after transplantation, with renal allograft function, although there are also conflicting findings [1,3,9,10,11,12,13,14,15,16,17,18,19,20]. The relationship between RI and transplant function and outcome may reflect intra-renal damage that can be of interest for evaluating the graft adequately.…”

Section: Introductionmentioning

confidence: 99%

Determinants of Resistive Index Shortly after Transplantation: Independent Relationship with Delayed Graft Function

Rodrigo¹,

López-Rasines

Ruiz³

et al. 2009

Nephron Clin Pract

View full text Add to dashboard Cite

Measurement of the vascular resistive index (RI) by Doppler ultrasonography has been proposed as a non-invasive method to evaluate renal allograft dysfunction, but there are conflicting reports about its clinical utility. The aim of our study was to analyse the donor and recipient characteristics related to RI measured at days 2 and 3 after renal transplantation and the relationship between RI and allograft outcome. RI was measured by Doppler ultrasonography in 333 patients at days 2 or 3 post-transplantation. Donor and recipient variables and allograft outcome were collected from a prospectively maintained institutional database. In patients with RI higher than 0.7, donor age, recipient age, duration of renal replacement therapy, incidence of diabetes, hypertension and atherosclerosis in the recipient, pulse pressure, initial creatinine and the incidence of delayed graft function (DGF) were higher. After multivariate analysis, the only variables that remained significant for an increased risk of higher RI were recipient age over 55 years, presence of diabetes in the recipient and DGF. Recipient age, previous diabetes mellitus and DGF are the most important determinants of transplant kidney RI in the first days after transplantation. So both the graft recipient and the graft itself, but not the donor, determine intra-renal Doppler indices.

show abstract

“…In the literature, the use of CDUS flow indices is reported mainly in the study of renal diseases [peak systolic velocity (PSV), pulsatility index (PI) and RI] [11].…”

Section: Discussionmentioning

confidence: 99%

Role of color Doppler ultrasound in the evaluation of renal transplantation from living donors

et al. 2014

View full text Add to dashboard Cite

Purpose The aim of this study was to evaluate the same kidney before and after transplantation to assess the ability of the allograft to restore blood flow, time required to achieve functional recovery after surgery and the possibility of differentiating normal from pathological allografts using color Doppler ultrasound (CDUS) flow indices: resistive index (RI)/renal cortical ratio (RCR) and scintigraphy. Materials and methods 79 living donors and 79 recipients. Donors underwent renal CDUS and scintigraphy. CDUS was repeated on the allograft 24 h, 3, 15 and 30 days after transplantation, and scintigraphy 3-5 days after transplantation. Recipients were divided into two groups on the basis of clinical and biochemical values: (A) well-functioning allografts and (B) acute pathology. Results of CDUS, RI and RCI were compared to results of scintigraphy, biochemical values and biopsy. Results Group (A) n = 60 (76 %), group (B) n = 19 (24 %); RI sensitivity was 93 %, specificity 83 %. In group (A) positive predictive value (PPV) was 94 % and in group (B) 90 %. RCR using receiver operating characteristic curve analysis yielded sensitivity 100 % and specificity 98.3 %. Scintigraphy mean values of glomerular filtration ratio and T max before transplantation were in group (A): 50.32 ml/min and 4.87 min; after transplantation 46.88 ml/ min and 4.96 min; in group (B): 48.68 ml/min and 4.63 min, after transplantation 27.89 ml/min and 10.53 min, respectively. Pearson's correlation coefficient between preoperative and postoperative results of scintigraphy was significant in group (A) (glomerular filtration ratio = 0.85, T max = 0.70) and not significant in group (B) (glomerular filtration ratio = 0.40, T max = 0.08). Conclusion This study shows that CDUS, RI and RCR are useful in postoperative evaluation of transplanted kidneys as these parameters can, after only 24 h, confirm the good condition of the allograft despite still excessive blood parameter values.Keywords Color Doppler Á Ultrasound Á Renal transplantation Á Living donor Á Blood flow indices Riassunto Scopo Scopo di questo studio è stato di valutare lo stesso rene prima e dopo il trapianto al fine di valutare la capacità dell'organo trapianto di ripristinare il flusso sanguigno, il tempo richiesto per raggiungere il recupero funzionale dopo l'intervento chirurgico e per differenziare nell'innesto il tessuto normale dal patologico con l'uso degli indici di flusso del color Doppler (CD): l'indice di resistenza (IR)/ renal cortical ratio (RCR) e la scintigrafia. Materiali e Metodi 79 donatori viventi e 79 riceventi. I donatori sono stati sottoposti a CD renale e a scintigrafia. Il CD è stato ripetuto sul tessuto trapiantato 24 ore, 3, 15 e 30 giorni dopo il trapianto e la scintigrafia, 3-5 giorni dopo il trapianto. I pazienti sono stati divisi in due gruppi sulla base dei dati clinici e biochimici: A) trapianto ben funzionante e B) patologia acuta. I risultati del CD, IR e RCR sono stati confrontati con i risultati della scintigrafia, i valori biochimici e la bio...

show abstract

Doppler Ultrasonographic Indices After Renal Transplantation as Renal Function Predictors

Cited by 25 publications

References 59 publications

Relation of Resistive and Pulsatility Indices With Graft Function After Renal Transplant

Relation of Resistive and Pulsatility Indices With Graft Function After Renal Transplant

Determinants of Resistive Index Shortly after Transplantation: Independent Relationship with Delayed Graft Function

Role of color Doppler ultrasound in the evaluation of renal transplantation from living donors

Contact Info

Product

Resources

About