Doppler Tissue Imaging Quantitates Regional Wall Motion During Myocardial Ischemia and Reperfusion

Dérumeaux, Geneviève; Ovize, Michel; Loufoua, Joseph; André‐Fouët, Xavier; Minaire, Y; Cribier, Alain; Letac, B

doi:10.1161/01.cir.97.19.1970

Cited by 285 publications

(156 citation statements)

References 50 publications

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“…Therefore, recent studies have recorded systolic motion velocities of the mitral annulus or the LV walls along the long axis by pulsed TDI using apical LV long-axis, 2-chamber and 4-chamber views to evaluate LV global [39] and regional [40][41][42] systolic function in patients with ischemic heart disease.…”

Section: Systolic Functionmentioning

confidence: 99%

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

Oki

2003

J Echocardiogr

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In general, pump function and myocardial contractility should be assessed when evaluating left ventricular (LV) systolic function. Ejection fraction obtained from left ventriculography is routinely used as an index of pump function, and the maximum value of the first derivative of LV pressure curve (peak dP/dt) has been used as an index of myocardial contractility. On the other hand, active relaxation of the LV myocardium during early diastole and LV passive filling or compliance during mid-to late diastole are important factors in evaluating LV diastolic function. To obtain this information, the time constant of the LV pressure decay during isovolumic diastole (tau) and LV end-diastolic pressure, which are calculated from the LV pressure curve recorded during cardiac catheterization, is used. However, invasive hemodynamic measurements cannot be performed in all patients, nor are they appropriate for follow-up evaluation involving repeated examinations.Recently, routine echocardiography has facilitated the noninvasive evaluation of LV systolic and diastolic function. The percent fractional shortening of the LV based on M-mode echocardiography and the LV ejection fraction determined by two-dimensional echocardiography are indices of LV pump function, and therefore cannot accurately evaluate LV myocardial contractility. On the other hand, "diastology" has become an important clinical topic [1]. There are several reasons why assessment of diastolic function is important: 1) 30 to 40% of patients evaluated for congestive heart failure have normal LV pump function [2,3]; 2) the transmitral flow velocity pattern, which is recorded using the pulsed Doppler method, may be an index for noninvasive evaluation of LV diastolic function [4]; and 3) the prognosis is poor in patients with LV systolic dysfunction and pseudonormalization or restrictive pattern of the transmitral flow velocity [5,6]. However, it has been shown that the diastolic indices obtained from transmitral and pulmonary venous flow velocities are influenced by loading conditions, especially by the pre- The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left AbstractThe widespread use of the pulsed Doppler echocardiography has facilitated the noninvasive evaluation of hemodynamic abnormalities of the left atrium and left ventricle (LV) based on transmitral and pulmonary venous flow velocity patterns. However, it has been shown that loading conditions, especially preload, influence the indices obtained from these velocity patterns. Recently, tissue Doppler imaging (TDI) has been applied to the clinical setting to assess LV myocardial function. In particular, this procedure has the following characteristics: 1) it can provide circumferential and longitudinal information for the LV myocardium; 2) the early diastolic LV myocardial parameters determined by TDI are not influenced by preload; 3) LV myocardial contractility can be evaluated from the early systolic parameters; 4) LV systolic and diastolic asynchrony can be detected; 5) myoca...

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Section: Systolic Functionmentioning

confidence: 99%

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

Oki

2003

J Echocardiogr

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“…It is worthy to note that only a few publications report data on the strain assessment by stress echocardiography in 2D Strain mode. Data of clinical and experimental studies demonstrate the possibility of assessing the parameters of the myocardial strain in stress echocardiography [6][7][8]. There is evidence that assessments of longitudinal and radial strains with Tissue Doppler Imaging [6,9] are sensitive to ischemia.…”

Section: Discussionmentioning

confidence: 99%

Assessment of Left Ventricular Mechanics in Patients with Ischemic Heart Disease

Гладких

Евтушенко

et al. 2016

MATEC Web Conf.

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Abstract. The paper presents new ultrasound technology for assessment of left ventricular (LV) strain in the longitudinal, radial, and circumferential directions and the LV area strain at rest and during dobutamine stressechocardiography in patients with intermediate pretest probability of ischemic heart disease (IHD). Analysis was performed for the first time using real-time three-dimensional echocardiography (4D Strain). It was shown that in patients with single-artery left anterior descending artery (LAD) and left circumflex coronary artery (LCX) stenosis of 50% and more, the decreases in the global LV strain in the longitudinal, radial, and circumferential directions as well as in the LV strain area were observed at peak dobutamine stress in 4D Strain mode. Assessment of global LV strain in 4D Strain mode during dobutamine test had low sensitivity, specificity, and diagnostic accuracy in diagnosing single-vessel coronary artery disease. Assessment of left ventricular mechanics in patients with ischemic heart diseaseMyocardial strain is currently considered a parameter characterizing left ventricular (LV) contractility [1]. Assessment of global LV strain in the longitudinal direction has been widely implemented in clinical practice based on speckle tracking imaging technology (2D Strain) [2]. Recently, three-dimensional real time imaging (4D Strain) was developed for assessment of LV strain. This approach consists in speckle tracking in three dimensions through time which requires the absence of motions beyond a plane of scanning. Due to this, 4D Strain can be considered a natural extension of 2D Strain [3]. Advantages of 4D Strain over 2D Strain are obvious: lower time expenditure due to feasibility of single-step strain assessment in all directions: longitudinal, radial, and circumferential [4], as well as supposedly better accuracy due to the absence of the fallout effect [3,5]. Therefore, 4D Strain study seems promising for early diagnosis of IHD. However, there is currently a lack of works showing the sensitivity, specificity, and diagnostic accuracy of the myocardial strain assessment by stress echocardiography in 4D Strain mode.

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“…[3][4][5][6][7][8][9][10] It is frequently observed in patients with CAD presenting with LV asynergy. [23][24][25] Earlier studies have demonstrated the presence of abnormal diastolic function in patients with CAD without evidence of systolic wall motion abnormalities by radionuclide angiography or digitized cineangiography. [26][27][28] Kondo et al have also demonstrated that delayed outward LV wall motion in the isovolumic relaxation phase by digital subtraction high-frame-rate echocardiography was indicative of CAD.…”

Section: Discussionmentioning

confidence: 99%

Detection of Diastolic Abnormality by Dyssynchrony Imaging Correlation With Coronary Artery Disease in Patients Presenting With Visibly Normal Wall Motion

Onishi

Uematsu

Nanto

et al. 2009

Circ J

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Background Post-systolic shortening (PSS) is a sensitive indicator of myocardial ischemia. Methods and ResultsWe have developed a tissue Doppler imaging technique that portrays PSS, and whether PSS correlates with coronary artery disease (CAD) was investigated in 186 patients presenting with chest pain and normal echocardiograms. Delays of the displacement peaks from end-systole were calculated in the apical views and displayed from green (0 ms) to red (≥100 ms): detection of diastolic abnormality by dyssynchrony imaging (DADI). CAD was judged positive by DADI when the left ventricular segments were color-coded red. Patients subsequently underwent thallium-201 myocardial perfusion single-photon emission computed tomography (n=150), coronary angiography (CAG, n=74), or both (n=37). CAD(-) was defined as negative scintigraphy test and/or no significant coronary artery stenosis by CAG. In 43 patients (23%), CAD(+) was confirmed by CAG as >75% diameter stenosis. DADI predicted CAD with sensitivity of 60%, specificity of 75%, predictive accuracy of 72%, positive predictive value of 42%, and negative predictive value of 86%. Among 74 patients who underwent CAG, sensitivity was best for the left anterior descending artery. Conclusions DADI detected the regional diastolic abnormality, which correlated with the presence of CAD in patients presenting with visibly normal wall motion. (Circ J 2009; 73: 125 -131)

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Doppler Tissue Imaging Quantitates Regional Wall Motion During Myocardial Ischemia and Reperfusion

Cited by 285 publications

References 50 publications

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

The Role of Tissue Doppler Imaging as a New Diagnostic Option in Evaluating Left Ventricular Function

Assessment of Left Ventricular Mechanics in Patients with Ischemic Heart Disease

Detection of Diastolic Abnormality by Dyssynchrony Imaging Correlation With Coronary Artery Disease in Patients Presenting With Visibly Normal Wall Motion

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