Doppler Echocardiographic Assessment of Pulmonary Prostheses: A Comprehensive Assessment Including Velocity Time Integral Ratio and Prosthesis Effective Orifice Area

Sadeghpour, Anita; Saadatifar, Hakimeh; Kiavar, Majid; Esmaeilzadeh, Maryam; Maleki, Majid; Ojaghi, Z; Noohi, Fereidoon; Samiei, Niloufar; Ahmad, Mahmood

doi:10.1111/j.1747-0803.2008.00223.x

Cited by 7 publications

(2 citation statements)

References 20 publications

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“…These data are consistent with those in our previous study on the peak pressure gradient and mean pressure gradient of mechanical pulmonary prostheses. 26 Interestingly, almost all the patients with prosthesis malfunction had significant prosthesis insufficiency (p< 0.001). In our opinion, new pulmonary prosthesis insufficiency could be a sign of prosthesis malfunction.…”

Section: Discussionmentioning

confidence: 96%

Mid-Term Outcome of Mechanical Pulmonary Valve Prostheses: The Importance of Anticoagulation

Sadeghpour¹,

Kyavar²,

Javani³

et al. 2014

J Cardiovasc Thorac Res

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Introduction: Pulmonary valve replacement (PVR) is being performed more commonly late after the correction of tetralogy of Fallot. Most valves are replaced with an allograft or xenograft, although reoperations are a common theme. Mechanical prostheses have a less favorable reputation due to the necessity of lifelong anticoagulation therapy and higher risk of thrombosis, but they are also less likely to require reoperation. There is a paucity of data on the use of prosthetic valves in the pulmonary position. We report the midterm outcomes of 38 cases of PVR with mechanical prostheses. Methods: One hundred twenty two patients who underwent PVR were studied. Thirty-eight patients, mean age 25 ± 8.4 years underwent PVR with mechanical prostheses based on the right ventricular function and the preferences of the patients and physicians. Median age of prosthesis was 1 year (range 3 months to 5 years). Results: Seven (18%) patients had malfunctioning pulmonary prostheses and two patients underwent redo PVR. Mean International Normalized Ratio (INR) in these seven patients was 2.1±0.8. Fibrinolytic therapy was tried and five of them responded to it well. There was no significant association between the severity of right ventricular dysfunction, patient’s age, prostheses valve size and age of the prosthesis in the patients with prosthesis malfunction. Conclusion: PVR with mechanical prostheses can be performed with promising midterm outcomes. Thrombosis on mechanical pulmonary valve prostheses remains a serious complication, but most prosthesis malfunction respond to fibrinolytic therapy, underscoring the need for adequate anticoagulation therapy.

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Section: Discussionmentioning

confidence: 96%

Mid-Term Outcome of Mechanical Pulmonary Valve Prostheses: The Importance of Anticoagulation

Sadeghpour¹,

Kyavar²,

Javani³

et al. 2014

J Cardiovasc Thorac Res

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“…1 (9). In general, most authors recommend porcine xenografts and homografts for the reconstruction of a competent pulmonary valve, that the late deterioration and reoperations are the rule (10).…”

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confidence: 99%

Mid-term follow-up of pulmonary valve bioprostheses in adults with congenital heart disease

Sadeghpour¹,

Javani²,

Peighambari³

et al. 2012

Anadolu Kardiyol Derg

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Tetralogy of Fallot

Sadeghpour

Alizadehasl

Mahdavi³

2014

Comprehensive Approach to Adult Congenital Heart Disease

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Doppler Echocardiographic Assessment of Pulmonary Prostheses: A Comprehensive Assessment Including Velocity Time Integral Ratio and Prosthesis Effective Orifice Area

Abstract: This study contributes to establishing the normal range for Doppler hemodynamics in various PVPs.

Cited by 7 publications

References 20 publications

Mid-Term Outcome of Mechanical Pulmonary Valve Prostheses: The Importance of Anticoagulation

Mid-Term Outcome of Mechanical Pulmonary Valve Prostheses: The Importance of Anticoagulation

Mid-term follow-up of pulmonary valve bioprostheses in adults with congenital heart disease

Tetralogy of Fallot

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