Doppler-Echocardiographic Assessment of Carbomedics Prosthetic Valves in the Mitral Position

Clinical and hemodynamic study of tilting disc heart valve: Single-center study

“…The results of our study clearly indicate that the performance of this valve is comparable to that of other tilting disc valves in current clinical use. [5][6][7][8] In the MVR group, although the incidence of infective endocarditis (1.08%) was higher in comparison to other published values of bileaflet and tilting disc valves, the incidences of valve thrombosis, embolism, and bleeding were comparable. Our high incidence of infective endocarditis can be attributed to the poor living conditions of the patients, ignorance, and injudicious use of antibiotics.…”

“…Studies conducted by others have provided valid values for gradients across various types of prosthetic valve. [4][5][6][7][8] In our study, the peak and mean gradients measured across TTK Chitra valves in aortic position were 33.8 AE 19.6 and 21.9 AE 11.2 mm Hg, 27.2 AE 10.5 and 16.5 AE 7.1 mm Hg, and 19.1 AE 0.9 and 8.9 AE 0.9 mm Hg for sizes 19, 21, and 23, respectively. For sizes 25, 27, 29, and 31 in the mitral position, the gradients were 18.7 AE 7.1 and 7.9 AE 4.5 mm Hg, 13.8 AE 6.2 and 5.4 AE 2.5 mm Hg, 9.5 AE 3.3 and 4.3 AE 0.9 mm Hg, and 6.3 AE 1.9 and 3.0 AE 0.7 mm Hg, respectively.…”

“…The peak and mean gradients and peak velocity across the valves in our series were comparable to other commonly used valves. 4–8 There was a definite shift in the NYHA class from II/III to I/II.…”

“…These values compare favorably with those of other valves. [4][5][6][7][8] Wilkins and colleagues 9 used continuous-wave Doppler echocardiography to measure gradients across mitral and tricuspid prosthetic valves, and obtained values that were equivalent to those calculated 10 There are various methods of calculating the EOA and each has merits and disadvantages. The continuity equation method and the pressure half-time method calculate an EOA that is less than the actual and geometric orifice area provided by the manufacturer.…”

“…These values compare favorably with those of other valves. [4][5][6][7][8] Wilkins and colleagues 9 used continuous-wave Doppler echocardiography to measure gradients across mitral and tricuspid prosthetic valves, and obtained values that were equivalent to those calculated 16 Carbomedics 0.25% 1.78% 0.85% 0.25% NA Toole 17 St. Jude Medical 3.2% 2.3% 2.3% 0.2% 0.7% Sezai 18 ATS 0.48% 0.16% NA by the invasive catheterization method, thus validating the use of color Doppler echocardiography for hemodynamic assessment. There have been various studies using the EOA as a tool for in-vivo valvular prosthesis assessment.…”