Dopamine sensor based on molecularly imprinted electrosynthesized polymers

Song, Wei; Chen, Yu; Xu, Juan; Yang, Xiaorong; Tian, Danbi

doi:10.1007/s10008-010-1025-9

Cited by 72 publications

(34 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Unlike in some previously reported studies, [15][16][17][18] the layer was less dense at higher template concentrations. When electropolymerization was performed at pH 7, the template could be removed, but rebinding at pH 7 was not observed.…”

contrasting

confidence: 85%

“…The imprinting factor was calculated to be 6.67 on the basis of the equation: imprinting factor = (signal of MIP)/(signal of NIP). The imprinting factor and the selectivity coefficients [13,18,20] were comparable with those of surface-imprinted MIPs. For bulk imprints, better values have been reported previously in a few cases, because a large number of "separation plates" results in more efficient separation.…”

mentioning

confidence: 58%

See 1 more Smart Citation

Coupling Biocatalysis with Molecular Imprinting in a Biomimetic Sensor

Yarman

Scheller

2013

Angew Chem Int Ed

View full text Add to dashboard Cite

Make it simple: A molecularly imprinted electropolymer was combined with an enzyme in a catalytic biomimetic sensor that enabled interference-free detection of the drug aminopyrine (AP) at submicromolar concentrations in the presence of ascorbic acid and uric acid within 15 s. The sensor functioned by the peroxide-dependent conversion of AP in a layer above a product-imprinted electropolymer on an indicator electrode.

show abstract

contrasting

confidence: 85%

mentioning

confidence: 58%

Coupling Biocatalysis with Molecular Imprinting in a Biomimetic Sensor

Yarman

Scheller

2013

Angew Chem Int Ed

View full text Add to dashboard Cite

show abstract

“…The imprinting factor was calculated to be 6.67 by the equation (Signal of MIP)/(Signal of NIP). The imprinting factor and the selectivity coefficients are comparable with those of surface imprinted MIPs in literature [21][22][23]. The fast response and also fast removal of the template is a remarkable advantage as compared with the harsh washing conditions and long times usually described for MIPs in literature [24].…”

Section: Removal Of the Template And Rebindingmentioning

confidence: 51%

Cytochrome c‐Derived Hybrid Systems Based on Moleculary Imprinted Polymers

et al. 2015

View full text Add to dashboard Cite

Hybrid architectures which combine a MIP with an immobilized “affinity ligand” or a biocatalyst sum up the advantages of both components. In this paper, hybrid architectures combining a layer of a molecularly imprinted electropolymer with a mini‐enzyme or a self‐assembled monolayer will be presented. (i) Microperoxidase‐11 (MP‐11) catalyzed oxidation of the drug aminopyrine on a product‐imprinted sublayer: The peroxide dependent conversion of the analyte aminopyrine takes place in the MP‐11 containing layer on top of a product‐imprinted electropolymer on the indicator electrode. The hierarchical architecture resulted in the elimination of interfering signals for ascorbic acid and uric acid. An advantage of the new hierarchical structure is the separation of MIP formation by electropolymerization and immobilization of the catalyst. In this way it was for the first time possible to integrate an enzyme with a MIP layer in a sensor configuration. This combination has the potential to be transferred to other enzymes, e.g. P450, opening the way to clinically important analytes. (ii) Epitope‐imprinted poly‐scopoletin layer for binding of the C‐terminal peptide and cytochrome c (Cyt c): The MIP binds both the target peptide and the parent protein almost eight times stronger than the non‐imprinted polymer with affinities in the lower micromolar range. Exchange of only one amino acid in the peptide decreases the binding by a factor of five. (iii) MUA‐poly‐scopoletin MIP for cytochrome c: Cyt c bound to the MIP covered gold electrode exhibits direct electron transfer with a redox potential and rate constant typical for the native protein. The MIP cover layer suppresses the displacement of the target protein by BSA or myoglobin. The combination of protein imprinted polymers with an efficient electron transfer is a new concept for characterizing electroactive proteins such as Cyt c. The competition with other proteins shows that the MIP binds its target Cyt c preferentially and that molecular shape and the charge of protein determine the binding of interfering proteins.

show abstract

“…There are many descriptions of using MIP films based on electropolymerisation of ophenylenediamine (o-PD) for determination of different kinds of templates, such as glucose (Cheng et al, 2001), sorbitol (Feng et al, 2004), DL-phenylalanine (Peng et al, 2001), theophylline (Kan et al, 2010), dopamine (Song et al, 2010), triclosan (Liu et al, 2009) singlestranded oligodeoxyribonucleotide (Tiwari et al, 2012), TnT and folic acid . Although, there are many reports of MIPs for small templates however, substantially less articles are published on MIPs for large templates, e.g.…”

Section: Introductionmentioning

confidence: 99%

Electrochemical evaluation of troponin T imprinted polymer receptor

Karimian

Turner

Tiwari

2014

Biosensors and Bioelectronics

View full text Add to dashboard Cite

The selective detection and quantification of macromolecular targets is a fundamental biological mechanism in nature. Molecularly imprinted polymers (MIPs) have been identified as one of the most promising synthetic alternatives to bioreceptors. However, expanding this methodology towards selective recognition of bulky templates such as proteins appears to be extremely challenging due to problems associated with removal of the template from the polymeric network. In this study, polymer imprinted with troponin T (TnT) was assessed using

show abstract

Dopamine sensor based on molecularly imprinted electrosynthesized polymers

Cited by 72 publications

References 31 publications

Coupling Biocatalysis with Molecular Imprinting in a Biomimetic Sensor

Coupling Biocatalysis with Molecular Imprinting in a Biomimetic Sensor

Cytochrome c‐Derived Hybrid Systems Based on Moleculary Imprinted Polymers

Electrochemical evaluation of troponin T imprinted polymer receptor

Contact Info

Product

Resources

About