Donation After Cardiac Death, a Possibility to Expand the Donor Pool: Review and the Hungarian Experience

Ghimessy, Áron; Farkas, Attila; Gieszer, Balázs; Radeczky, Péter; Csende, Kristóf; Mészáros, László; Török, Klára; Fazekas, Levente; Acsády, László; Kocsis, Ákos; Bartók, Tibor; Dancs, Tamás; Tóth, Krisztina; Schönauer, Nóra; Madurka, Ildikó; Elek, Jenö; Döme, Balázs; Rényi-Vámos, F; Láng, György; Taghavi, Shahrokh; Hötzenecker, Konrad; Klepetko, Walter; Bogyó, Levente

doi:10.1016/j.transproceed.2019.04.003

Cited by 3 publications

(1 citation statement)

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“…Loss of cardiopulmonary function is documented by e.g., echocardiography, electrocardiogram, and invasive monitoring of pulse and blood pressure (35). The period of non-intervention is variable and extends from seconds to several minutes (35)(36)(37). Circulation is then restored, involving cannulation and extracorporeal membrane oxygenation, and organs are explanted.…”

Section: Donation After Circulatory Death (Dcd)mentioning

confidence: 99%

The Neurology of Death and the Dying Brain: A Pictorial Essay

Kondziella

2020

Front. Neurol.

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As neurologists earn their living with the preservation and restoration of brain function, they are also well-positioned to address the science behind the transition from life to death. This essay in pictures highlights areas of neurological expertise needed for brain death determination; shows pitfalls to avoid during the clinical examination and interpretation of confirmatory laboratory tests in brain death protocols; illustrates the great variability of brain death legislations around the world; discusses arguments for the implementation of donation after circulatory death (DCD); points to unresolved questions related to DCD and the time between cardiac standstill and organ procurement ("hands-off period"); provides an overview of the epidemiology and semiology of near-death experiences, including their importance for religion, literature, and the visual arts; suggests biological mechanisms for near-death experiences such as dysfunction of temporoparietal cortex, N-methyl-D-aspartate receptor antagonism, migraine aura, and rapid eye movement sleep; hypothesizes that thanatosis (aka. death-feigning, a common behavioral trait in the animal kingdom) represents the evolutionary origin of neardeath experiences; and speculates about the future implications of recent attempts of brain resuscitation in an animal model. The aim is to provide the reader with a thorough understanding that the boundaries within the neurology of death and the dying brain are being pushed just like everywhere else in the clinical neurosciences.

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