Despite over 50 years of messaging about the reality of human-caused climate change, substantial portions of the population remain sceptical. Furthermore, many sceptics remain unmoved by standard science communication strategies, such as myth busting and evidence building.To understand this, we examine psychological and structural reasons why climate change misinformation is prevalent. First, we review research on motivated reasoning: how interpretations of climate science are shaped by vested interests and ideologies. Second, we examine climate scepticism as a form of political followership. Third, we examine infrastructures of disinformation: the funding, lobbying and political operatives that lend climate scepticism its power. Guiding this Review are two principles: (1) to understand scepticism, one must account for the interplay between individual psychologies and structural forces; and (2) global data are required to understand this global problem. In the spirit of optimism, we finish by describing six strategies for reducing the destructive influence of climate scepticism.Decades ago, scientists reached consensus that human activities are changing the Earth's climate and that these changes will have dramatic, largely negative consequences. This message has been a prominent and persistent feature of the global conversation, occupying policymakers at all levels. Nonetheless, a sizeable-and frequently vocal-minority of the population continues to argue that the scientists are wrong. At the turn of the century, the main contrarian claim was that temperatures are not rising 1 . A sequence of record-breaking global temperatures during the next two decades forced a shift in the narrative of climate sceptics: yes, temperatures are rising, but human activities are not a primary cause of it 2 . Over time, new elements were added to the spectrum of arguments: that climate change will be benign, that the issue has been exaggerated or that known mitigation methods are ineffective 2,3 . Uniting these arguments are three features: (1) they defy the overwhelming scientific consensus; (2) they slow our collective ability to respond to the climate crisis; and (3) the number of people who hold them is too big to ignore. For example, in Australia (a world-leading exporter of coal) and the United States (the second biggest carbon emitter in the world) roughly one-third of the population maintains that climate change is not predominantly caused by humans [4][5][6] . Surveys from South America indicate wide variability in levels of scepticism across nations, but 40-50% of respondents in Honduras, Dominican Republic and Ecuador agreed with the statement 'Climate change is not a problem' 7 .In trying to understand this phenomenon, one line of thought subscribes to a deficit argument: perhaps climate change scepticism is due to lack of education or scientific literacy. Research suggests a kernel of truth in this argument, and there is a long history of finding positive effects of interventions designed to address information deficit...