Domestic Environment and Gut Microbiota: Lessons from Pet Dogs

Hernandez, Juan; Rhimi, Soufien; Kriaa, Aïcha; Mariaule, Vincent; Boudaya, Houda; Drut, Amandine; Jablaoui, Amin; Mkaouar, Héla; Saidi, Amel; Biourge, Vincent; Borgi, Mohamed Ali; Rhimi, Moez; Maguin, Emmanuelle

doi:10.3390/microorganisms10050949

Cited by 15 publications

(10 citation statements)

References 122 publications

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“…1b). Overall, these bacterial abundances appear to be similar to those reported in other dogs, which suggests the existence of typical oral and gut microbiota in these animals (Ruparell et al 2020;Hernandez et al 2022).…”

Section: Oral and Gut Microbiota Analysed In This Studysupporting

confidence: 81%

Characterization of the oral and faecal microbiota associated with atopic dermatitis in dogs selected from a purebred Shiba Inu colony

Uchiyama

Osumi

Mizukami

et al. 2022

Letters in Applied Microbiology

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Atopic dermatitis (AD) is a chronic and relapsing multifactorial inflammatory skin disease that also affects dogs. The oral and gut microbiota are associated with many disorders, including allergy. Few studies have addressed the oral and gut microbiota in dogs, although the skin microbiota has been studied relatively well in these animals. Here, we studied the AD‐associated oral and gut microbiota in 16 healthy and 9 AD dogs from a purebred Shiba Inu colony. We found that the diversity of the oral microbiota was significantly different among the dogs, whereas no significant difference was observed in the gut microbiota. Moreover, a differential abundance analysis detected the Family_XIII_AD3011_group (Anaerovoracaceae) in the gut microbiota of AD dogs; however, no bacterial taxa were detected in the oral microbiota. Third, the comparison of the microbial co‐occurrence patterns between AD and healthy dogs identified differential networks in which the bacteria in the oral microbiota that were most strongly associated with AD were related to human periodontitis, whereas those in the gut microbiota were related to dysbiosis and gut inflammation. These results suggest that AD can alter the oral and gut microbiota in dogs.

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Section: Oral and Gut Microbiota Analysed In This Studysupporting

confidence: 81%

Characterization of the oral and faecal microbiota associated with atopic dermatitis in dogs selected from a purebred Shiba Inu colony

Uchiyama

Osumi

Mizukami

et al. 2022

Letters in Applied Microbiology

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“…While insights suggest that Inuit dogs have retained genetic markers unique to their indigenous history, these breeds have occupied overlapping geographical regions as sled dogs since the European colonization of the Arctic ( 109 , 110 ). Multiple studies have shown that gut microbial composition depends on environment ( 18 , 111 ), which may contribute to similarities in microbiota among dogs in this study. Careful longitudinal analysis of multiple samples from before and after intense activity and with and without glucosamine supplementation will likely provide further insights into the influence of these variables on microbiome composition.…”

Section: Discussionmentioning

confidence: 81%

Analysis of the gut microbiome in sled dogs reveals glucosamine- and activity-related effects on gut microbial composition

Wang,

Russel,

Macdonald

et al. 2024

Front. Vet. Sci.

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The composition of the microbiome influences many aspects of physiology and health, and can be altered by environmental factors, including diet and activity. Glucosamine is a dietary supplement often administered to address arthritic symptoms in humans, dogs, and other mammals. To investigate how gut microbial composition varies with glucosamine supplementation, we performed 16S rRNA sequence analysis of fecal samples from 24 Alaskan and Inuit huskies and used mixed effects models to investigate associations with activity, age, and additional factors. Glucosamine ingestion, age, activity, sex, and diet were correlated with differences in alpha-diversity, with diversity decreasing in dogs consuming glucosamine. Beta-diversity analysis revealed clustering of dogs based on glucosamine supplementation status. Glucosamine supplementation and exercise-related activity were associated with greater inter-individual pairwise distances. At the family level, Lactobacillaceae and Anaerovoracaceae relative abundances were lower in supplemented dogs when activity was accounted for. At the genus level, Eubacterium [brachy], Sellimonus, Parvibacter, and an unclassified genus belonging to the same family as Parvibacter (Eggerthellaceae) all were lower in supplemented dogs, but only significantly so post-activity. Our findings suggest that glucosamine supplementation alters microbiome composition in sled dogs, particularly in the context of exercise-related activity.

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“…Domestic dogs share the house with the owners. Its microbiota has a taxonomic similarity with humans, much larger than mice or pig (73,74). Living or working with another type of animals may in uence the human microbiota, too, due to their different speci c microbiota.…”

Section: Discussionmentioning

confidence: 99%

Systematic review of factors influencing human digestive microbiota in healthy adults and interactions between them

Pérez-Llano,

Rodriguez,

Fraile

2024

Preprint

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Introduction: Human digestive microbiota is affected by a wide variety of different factors. The objective of this study was to perform a systematic review that gathers and updates the information available about factors that affect human digestive microbiota in healthy adults older than 19 years. It is also reviewed the way to recover data about these factors in every study to know which of these factors are considered and if some type of interaction between them is studied. Methods: We systematically searched MEDLINE, Web of Science, Scielo, PROSPERO, and Cochrane databases for relevant articles on factors that affect human digestive microbiota. Two authors independently reviewed study eligibility and data extraction. Articles were classified based on the studied factor upon one of the following categories: diet, habits, environment, or chemical exposure. Results: 41 of the articles included a questionnaire addressing factors affecting the human microbiota. We collected the data from the questionnaires used in these studies and analyzed the presence of data about diet, habits, environment, and exposition to chemicals. Analysis of the studies indicates that the assessment of risk factors is often partial or focused on a specific aspect (diet, habits, environment, and chemicals). In addition, there are some factors relevant to the human digestive microbiota that are not being assessed (type of fermentation meals, UP foods consumption, vitamin D administration, snacking, intermittent fasting, the number of daily intakes, type of sport practiced, living with pets or working with another type of animals, type of transportation daily used, place of work, home cleaning habits, treatments with radiotherapy, immune suppressants, corticosteroids, and anovulatory). Discussion: Little is known about the impact of the combined interaction of possible risk factors (diet, habits, environment, and chemical exposure). Further studies are encouraged to evaluate more broadly the risk factors that may influence the diversity of the human digestive microbiota and their interactions.

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Domestic Environment and Gut Microbiota: Lessons from Pet Dogs

Cited by 15 publications

References 122 publications

Characterization of the oral and faecal microbiota associated with atopic dermatitis in dogs selected from a purebred Shiba Inu colony

Characterization of the oral and faecal microbiota associated with atopic dermatitis in dogs selected from a purebred Shiba Inu colony

Analysis of the gut microbiome in sled dogs reveals glucosamine- and activity-related effects on gut microbial composition

Systematic review of factors influencing human digestive microbiota in healthy adults and interactions between them

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