Domestic allergens in public places II: dog (Can f 1) and cockroach (Bla g 2) allergens in dust and mite, cat, dog and cockroach allergens in the air in public buildings

Cockroach allergy has been recognized as an important cause of asthma. Exposure to high levels of cockroach allergens in the home is a major risk factor for symptoms in sensitized individuals. Previously identified allergens from Blatella germanica and Periplaneta americana include Bla g 2 (inactive aspartic proteinase), Bla g 4 (calycin), Bla g 5 (glutathione-S-transferase), Bla g 6 (troponin), the Group 1 cross-reactive allergens Bla g 1 and Per a 1, Per a 3 (arylphorin), and Per a 7 (tropomyosin). The primary site of cockroach allergen accumulation is the kitchen. However, lower levels of allergen can be found in bedding, on the bedroom floor, and in sofa dust. Strategies for decreasing exposure to cockroach have been investigated. The results suggest that a sustained decrease in cockroach allergen levels is difficult to accomplish, even after successful extermination of cockroach populations. The use of recombinant cockroach allergens may lead to the development of new approaches to asthma treatment in the future.

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“…In British schools, 65% of the classrooms sampled had levels of cockroach allergen Bla g 2 >2 U/g of dust [32].…”

Section: Characteristics Of Cockroach Allergensmentioning

confidence: 99%

Cockroach allergens: Environmental distribution and relationship to disease

Arruda

Ferriani²,

Vailes³

et al. 2001

Curr Allergy Asthma Rep

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“…The small particles of cat and dog allergen can scatter easily in the air and adhere to clothing for further dispersal [40,41]. These allergens are found in non-pet homes [42,43], schools [41,44,45] and public places [44]. As such, similar prevalence of sensitivity is found in children who live with a cat and those who do not [28].…”

Section: Petmentioning

confidence: 91%

Reprint of: Perinatal and early childhood environmental factors influencing allergic asthma immunopathogenesis

Gaffin

Kanchongkittiphon

Phipatanakul

2014

International Immunopharmacology

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“…A difficulty in performing these studies has been developing accurate methods for quantifying pet exposure. Studies have shown that cat and dog allergens are ubiquitous, even in homes where pets are not kept and in public buildings such as schools, day care centers, office buildings, and hospitals where pets are not commonly allowed [36][37][38][39]. In addition, children are commonly exposed to pets outside the home, including the homes of friends and relatives and in-home day care centers.…”

Section: Ubiquity Of Pet Allergensmentioning

confidence: 97%