Dome-Shaped Periorbital Papule

Abstract

A 76-year-old woman presented with a slowly growing, asymptomatic, 5-mm, pink-brown, dome-shaped papule adjacent to the left lateral canthus of several years' duration. Dermoscopic examination revealed fine linear peripheral blood vessels. The lesional cells were positive with cytokeratin 7, estrogen receptor, progesterone receptor, chromogranin, synaptophysin, and neuron-specific enolase. Cytokeratin 20 and p63 were negative, and the Ki-67 proliferative index was less than 5%. THE BEST DIAGNOSIS IS:a. apocrine hidrocystoma b. basal cell carcinoma (adenoid type) c. endocrine mucin-producing sweat gland carcinoma d. microcystic adnexal carcinoma e. primary cutaneous adenoid cystic carcinoma