Domains rated as important by patients with hand osteoarthritis

Leung, Ying Ying; Li, Justin Chung-Hin; Thumboo, Julian

doi:10.1111/1756-185x.13709

Cited by 4 publications

(2 citation statements)

References 34 publications

(46 reference statements)

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“…Although this approach has been demonstrated to be effective and is currently recommended, a consistent proportion of patients fails to reach the target owing to PROs included in the aforementioned indexes. [23][24][25] Other relevant topics were the importance of nutrition and physical activity. This is in line with the EULAR recommendations: physical activity can be useful to improve pain, fatigue, sleep quality and emotional well-being.…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, control of disease activity is considered pivotal for rheumatologists and clinimetric parameters, such as disease activity score for rheumatoid arthritis, disease activity for psoriatic arthritis or for ankylosis spondylitis, are routinely used to evaluate disease activity through treat‐to‐target and tight control strategies. Although this approach has been demonstrated to be effective and is currently recommended, a consistent proportion of patients fails to reach the target owing to PROs included in the aforementioned indexes 23‐25 …”

Section: Discussionmentioning

confidence: 99%

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Relevant non‐pharmacologic topics for clinical research in rheumatic musculoskeletal diseases: The patient perspective

et al. 2020

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Objective: The research approach on rheumatic musculoskeletal diseases (RMDs) is challenging and patient involvement is an emerging issue to obtain relevant information to research. Despite growing interest in non-pharmacologic aspects of clinical research in RMDs, the patients' perspectives are currently poorly explored. Methods: A cross-sectional no-profit online survey was devised to identify and rank the priorities for clinical research in RMDs according to patients' perspectives. Patients were asked to rate the following topics: food/nutrition, air pollution, smoking, work activity, social participation, physical activity, emotional well-being/stress, alternative medicine, and patient-physician relationship. The survey was disseminated by ALOMAR (Lombard Association for Rheumatic Diseases) between June and October 2019. Results: Two hundred RMD patients completed the survey. The topic most rated 188 (94%) was the doctor-patient relationship, considered very or extremely important. Other topics rated as follows: psychological well-being 185 (92.5%), physical activity 155 (77.5%), nutrition, eating habits 150 (75%), alternative therapies 144 (72%), work activity 144 (72%), environmental pollution 134 (67%), social life 121 (60.5%) and cigarette smoke 119 (59.5%). The topics considered relevant were perceived to be able to influence disease symptoms. Environmental pollution and smoking were considered the most important for RMD prevention in 43.3% and 48.7% respectively. Conclusions: This survey highlights the relevance of several unmet needs and indicates that active patient involvement is essential to design successful translational studies and improve clinical outcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Relevant non‐pharmacologic topics for clinical research in rheumatic musculoskeletal diseases: The patient perspective

et al. 2020

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Comparative effectiveness of pharmacological interventions for hand osteoarthritis: a systematic review and network meta-analysis of randomised trials

Døssing,

Nielsen,

Kroon

et al. 2023

RMD Open

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ObjectiveTo explore the comparative effectiveness of pharmacological interventions for hand osteoarthritis (OA).MethodsWe systematically searched Embase, MEDLINE, and the Cochrane Central Register of Controlled Trials from inception until 26 December 2021, for randomised trials of pharmacological interventions for people with hand OA. Two reviewers independently extracted study data and assessed the risk of bias. We calculated the effect sizes for pain (standardised mean differences) using Bayesian random effects models for network meta-analysis (NMA) and pairwise meta-analysis. Based on a pre-specified protocol, we prospectively registered the study at PROSPERO, CRD42021215393.ResultsWe included 72 trials with 7609 participants. 65 trials (n=5957) were eligible for the quantitative synthesis, investigating 29 pharmacological interventions. Oral non-steroidal anti-inflammatory drugs (NSAIDs) and oral glucocorticoids’ NMA effect sizes were −0.18 (95% credible interval −0.36 to 0.02) and −0.54 (−0.83 to −0.24), respectively, compared with placebo, and the result was consistent when limiting evidence to the pairwise meta-analysis of trials without high risk of bias. Intra-articular hyaluronate, intra-articular glucocorticoids, hydroxychloroquine, and topical NSAIDs’ NMA effect sizes were 0.22 (−0.08 to 0.51), 0.25 (0.00 to 0.51), −0.01 (−0.19 to 0.18), and −0.14 (−0.33 to 0.08), respectively, compared with placebo. Oral NSAIDs were inferior to oral glucocorticoids with an NMA effect size of 0.36 (0.01 to 0.72). No intervention was superior to placebo when stratifying for thumb and finger OA.ConclusionOral NSAIDs and glucocorticoids are apparently effective pharmacological interventions in hand OA. Intra-articular therapies and topical NSAIDs were not superior to placebo.

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Person-centred care in osteoarthritis and inflammatory arthritis: a scoping review of people’s needs outside of healthcare

Fairley

Seneviwickrama

Yeh

et al. 2021

BMC Musculoskelet Disord

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Background Arthritis, regardless of cause, has significant physical, social and psychological impacts on patients. We aimed to identify the non-healthcare needs perceived by patients with inflammatory arthritis (IA) and osteoarthritis (OA), and to determine if these differ. Methods We electronically searched MEDLINE, PsycINFO, EMBASE and CINAHL (1990–2020) systematically to identify non-healthcare-related needs of people with IA or OA. All citations were screened and quality appraised by two reviewers. Data was extracted by a single reviewer. Results The search identified 7853 citations, with 31 studies included (12 for OA, 20 for IA). Six areas of need emerged and these were similar in both group These were: 1) Assistance with activities of daily living especially related to a lack of independence; 2) Social connectedness: need for social participation; 3) Financial security: worry about financial security and increased costs of health-seeking behaviours; 4) Occupational needs: desire to continue work for financial and social reasons, facilitated by flexibility of workplace conditions/environment; 5) Exercise and leisure: including limitation due to pain; 6) Transportation: limitations in ability to drive and take public transport due to mobility concerns. Many areas of need were linked; e.g. loss of employment and requiring support from family was associated with a sense of “failure” and loss of identity, as social isolation. Conclusions This review highlights the pervasive impact of arthritis on peoples’ lives, regardless of aetiology, albeit with a limited evidence base. Improved identification and targeting of non-healthcare needs of people with arthritis is likely to improve person-centred care.

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Domains rated as important by patients with hand osteoarthritis

Cited by 4 publications

References 34 publications

Relevant non‐pharmacologic topics for clinical research in rheumatic musculoskeletal diseases: The patient perspective

Relevant non‐pharmacologic topics for clinical research in rheumatic musculoskeletal diseases: The patient perspective

Comparative effectiveness of pharmacological interventions for hand osteoarthritis: a systematic review and network meta-analysis of randomised trials

Person-centred care in osteoarthritis and inflammatory arthritis: a scoping review of people’s needs outside of healthcare

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