Dog model for study of supracrestal bone apposition around partially inserted implants

Abstract

A dog model for study of supracrestal bone growth around partially inserted implants is described. The mandibular premolar teeth (P1, P2, P3 and P4) were extracted on both sides of the mandible in four dogs. At a surgical exposure 12 weeks later, two 10 mm titanium implants were partially inserted on each side, 15 mm apart, in the areas of the P1 and the P3 so that five threads protruded from the bone crest. A titanium mesh was fastened to the coronal aspect of the two fixtures and covered with an ePTFE membrane. Thus, a space for potential bone formation was created between the two implants. The surgical flaps were coronally positioned and secured with vertical mattress sutures. After 12 weeks of healing, biopsy specimens were retrieved and examined histologically. In three of the four dogs under study, the partially inserted implants had integrated and the intended large wound spaces had been created around the noninserted parts of the implants. However, bone was not formed around the protruding implants. Accordingly, this experimental model may prove useful for future studies on the use of various procedures that hypothetically may enhance bone formation.

Clinical outcomes of vertical bone augmentation to enable dental implant placement: a systematic review

“…Four papers within the total 18 studies described GBR by means of an e‐PTFE membrane and blood clot in a one‐stage procedure. Two of them (Simion et al 1994, Jovanovic et al 1995) reported a significant mean vertical bone gain in respect to the control sites, whereas the other two papers (Roos‐Jansåker et al 2002, Stenport et al 2003) failed to demonstrate such a difference compared with the controls.…”

Vertical ridge augmentation with guided bone regeneration in association with dental implants: an experimental study in dogs

“…Roos‐Jansaker et al (2002) described a canine model where a large wound space was produced coronal to a non‐reduced alveolar crest by means of two partially inserted implants and a titanium mesh fixed to the coronal aspect of the implants. However, newly formed bone in direct contact with the exposed threads was not observed in any of the examined wound spaces.…”

Failure to induce supracrestal bone growth between and around partially inserted titanium implants using bone morphogenetic protein (BMP): an experimental study in dogs

“…Five threads were left non‐submerged coronal to the surrounding bone and a titanium mesh was attached to the implants, creating a large space potentially allowing for new bone formation. The design of our study is similar to that used in a previous publication by Roos‐Jansåker et al (2002). Roos‐Jansåker et al demonstrated that the model as such did not create coronal bone growth either around the implants or in the large wound area between the implants.…”