Does Vitamin D Status Affect the Attainment of In-Hospital Functional Milestones After Total Hip Arthroplasty?

Unnanuntana, Aasis; Rebolledo, Brian J.; Gladnick, Brian P.; Nguyen, Joseph; Sculco, Thomas P.; Cornell, Charles N.; Lane, Joseph M.

doi:10.1016/j.arth.2011.05.023

Cited by 43 publications

(51 citation statements)

References 41 publications

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“…This particular finding agrees with previous reports [5,13,24,25]. However, in contrast to previous reports, we did not find associations between insufficiency and any other baseline patient characteristic (age, sex, race, comorbidities) (regardless of the threshold used) [5,24,25]. Bogunovic et al [5] found that patients between the ages of 18 and 50 years were at more risk of having inadequate vitamin D levels (p = 0.018), as well as male sex and patients with darker skin tone (black and Hispanics) (p \ 0.001 for both).…”

Section: Discussionsupporting

confidence: 94%

“…Regarding insufficiency and baseline patient characteristics, our patients with insufficiency had higher BMI (using the 20-ng/mL threshold). This particular finding agrees with previous reports [5,13,24,25]. However, in contrast to previous reports, we did not find associations between insufficiency and any other baseline patient characteristic (age, sex, race, comorbidities) (regardless of the threshold used) [5,24,25].…”

Section: Discussionsupporting

confidence: 88%

“…Our findings are in agreement with the literature [5,15,18,24,25]. Bogunovic et al [5] (using a 32-ng/ mL cutoff) found that 43% of patients undergoing orthopaedic surgery had subnormal levels.…”

Section: Discussionsupporting

confidence: 83%

“…Unnanuntana et al [25] found that there were more women with normal levels and more men with subnormal levels (p = 0.008). Unnanuntana et al [24], in a separate study of three groups (deficiency, insufficiency, and normal), found that the proportion of patients who had an ASA score of 3 or 4 was significantly higher in patients with deficiency (52.9%, 22.6%, and 23.9%, respectively, p = 0.032). We only found associations with BMI.…”

Section: Discussionmentioning

confidence: 96%

“…Even though hypovitaminosis D is the accepted term for insufficient or deficient levels [18], in view of the current lack of consensus on what level defines the low end of the normal range (and much more on the derived terms), we will refer to all patients with subnormal levels as patients with insufficiency for the sake of simplicity. What appears clear is that this vitamin is associated with a number of diseases [16,18,26] and, in some reports, with poorer results after surgery [14,15,18]; however, findings on the latter point have varied among studies [24,25].…”

Section: Introductionmentioning

confidence: 99%

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Vitamin D Insufficiency in Patients With THA: Prevalence and Effects on Outcome

Lavernia

Villa

Iacobelli

et al. 2013

Clin Orthop Relat Res

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Background The consequences of vitamin D insufficiency in the elderly remain controversial. The prevalence and potential effects of its chronic insufficiency on quality of life and physical function in patients undergoing THA have received little attention.Question/purposes We determined (1) prevalence of preoperative vitamin D insufficiency in patients undergoing THA and (2) relationships of insufficiency to patientperceived outcomes (PPOs) and hip scores. Methods We retrospectively reviewed 62 consecutive patients who underwent 66 primary THAs. We excluded two patients with missing data and the second hip of bilateral THAs, leaving 60 patients (60 hips) for final inclusion. Based on preoperative plasma 25-hydroxyvitamin-D3 levels, patients were retrospectively assigned into a normal or insufficient group. We used two different thresholds (20 and 30 ng/mL) to define insufficiency; groups were set twice. We compared demographics, BMI, American Society of Anesthesiologists score, Charlson Comorbidity Index; albumin, transferrin, calcium levels; and total lymphocyte count between groups. The insufficient group had a higher mean BMI with the 20-ng/mL cutoff but not with the 30-ng/mL cutoff. We compared the 20-ng/mL cutoff groups (adjusting for BMI) and the 30-ng/mL cutoff groups in terms of preoperative and postoperative Quality of Well-being Scale, SF-36, WOMAC, Harris hip, and Merle d'Aubigné-Postel scores. Mean followup was 11 months (range, 3-24 months). Results The prevalence of vitamin D insufficiency was 30% (using 20 ng/mL) and 65% (using 30 ng/mL). Preoperative and postoperative Harris hip and Merle d'Aubigné-Postel scores were lower in patients with

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 88%

Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 96%

Section: Introductionmentioning

confidence: 99%

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Vitamin D Insufficiency in Patients With THA: Prevalence and Effects on Outcome

Lavernia

Villa

Iacobelli

et al. 2013

Clin Orthop Relat Res

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High rates of vitamin D insufficiency among patients presenting for total knee arthroplasty

Liu,

Seyok,

Moye

et al. 2024

Journal Orthopaedic Research

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Widely varying prevalence of vitamin D deficiency has been reported in patients presenting for total knee arthroplasty (TKA). The primary aim of this study was to determine vitamin D levels in TKA patients and to compare to patients already routinely evaluated for vitamin D levels, patients with fragility fractures of the distal radius (DRF). There is significant overlap between patients presenting for TKA and with DRF, both in terms of medical comorbidities and overall health status, making these populations suitable comparative cohorts. Wefound that all patients presenting for TKA consultation had vitamin D insufficiency and 33% had vitamin D deficiency, compared to only 37% and 14% in the DRF cohort, a patient population routinely evaluated for vitamin D due to the high risk of deficiency. Furthermore, patients with DRF had higher levels of vitamin D before (38 ± 16 vs. 23 ± 5) and after vitamin D supplementation (39 ± 17 vs. 33 ± 10), suggesting that patients presenting for TKA are at even higher risk of vitamin D insufficiency than patients presenting with DRF. Reassuringly, supplementation successfully corrected 39.0% and 55.8% of patients in the DRF and TKA cohorts, respectively.

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Bone Health and Orthopedic Surgery

Russell

2014

Perioperative Care of the Orthopedic Patient

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Does Vitamin D Status Affect the Attainment of In-Hospital Functional Milestones After Total Hip Arthroplasty?

Cited by 43 publications

References 41 publications

Vitamin D Insufficiency in Patients With THA: Prevalence and Effects on Outcome

Vitamin D Insufficiency in Patients With THA: Prevalence and Effects on Outcome

High rates of vitamin D insufficiency among patients presenting for total knee arthroplasty

Bone Health and Orthopedic Surgery

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