Does Turmeric/curcumin Supplementation Change Anthropometric Indices in Patients with Non-alcoholic Fatty Liver Disease? A Systematic Review and Meta-analysis of Randomized Controlled Trials

Jafarirad, Sima; Mansoori, Anahita; Adineh, Ahmad; Panahi, Yunes; Hadi, Amir; Goodarzi, Reza

doi:10.7762/cnr.2019.8.3.196

Cited by 21 publications

(19 citation statements)

References 60 publications

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“…No significant effect of turmeric/curcumin on body weight and BMI in NAFLD patients was described by Jafarirad et al [ 205 ]; however, the last dose–response meta-analysis [ 206 ] (n-8 RCTs) showed that curcumin might positively affect the visceral fat and abdominal obesity. The beneficial systemic/metabolic effects of orally administered curcumin are also related to their influence on the microbial community.…”

Section: New Dietary Perspectives In Nafld Treatment Via Gm Modulamentioning

confidence: 99%

Nutritional Approach Targeting Gut Microbiota in NAFLD—To Date

Moszak

Szulińska

Walczak-Gałęzewska

et al. 2021

IJERPH

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Non-alcoholic fatty liver disease (NAFLD) is a significant clinical and epidemiological problem that affects around 25% of the adult global population. A large body of clinical evidence highlights that NAFLD is associated with increased liver-related morbidity and mortality and an increased risk of cardiovascular disease, extrahepatic cancers, type 2 diabetes, and chronic kidney disease. Recently, a series of studies revealed the pivotal role of gut microbiota (GM) dysbiosis in NAFLD’s pathogenesis. The GM plays an essential role in different metabolic pathways, including the fermentation of diet polysaccharides, energy harvest, choline regulation, and bile acid metabolism. One of the most critical factors in GM stabilization is the diet; therefore, nutritional therapyappearsto be a promising tool in NAFLD therapy. This paper aims to review the current knowledge regardingthe nutritional approach and its implications with GM and NAFLD treatment. We discuss the positive impact of probiotics, prebiotics, and symbiotics in a reverse dysbiosis state in NAFLD and show the potential beneficial effects of bioactive substances from the diet. The full description of the mechanism of action and comprehensive examination of the impact of nutritional interventions on GM modulation may, in the future, be a simple but essential tool supporting NAFLD therapy.

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Section: New Dietary Perspectives In Nafld Treatment Via Gm Modulamentioning

confidence: 99%

Nutritional Approach Targeting Gut Microbiota in NAFLD—To Date

Moszak

Szulińska

Walczak-Gałęzewska

et al. 2021

IJERPH

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“…Even though turmeric is believed has a good impact on health, but studies found that it has a side effect. It could cause headaches, rash, and diarrhea (Jafarirad et al, 2019).…”

Section: Traditional Medicationmentioning

confidence: 99%

Traditional Medicine for Children among Kaluppini Indigenous People in South Sulawesi

Nurbaya

Chandra²,

Hapsari

2020

ETNOSIA

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The traditional knowledge about the use of ancestral medicines to cure children was highly valued by the indigenous community and an essential part of their indigenous health system. This study aimed to provide insight into the traditional medication using plant-based medication to children in an indigenous community in South Sulawesi Province. This study was conducted in Kaluppini Village, Enrekang Regency, South Sulawesi. In-depth interviews and focus group discussions were conducted both in Bahasa Indonesia and the local language. Informants were traditional birth attendants and mothers of under-five. This study was carried out from January to June 2018. Data were analyzed using thematic coding. It is found that Kaluppini mothers have traditional knowledge of treatment. They used kinds of plants as traditional remedies to cure their children. This traditional medication named as pembollo’ and pejappi. Pembollo’ are traditional plants intended to cure sick children. Kaluppini people believe that pejappi is a collection of traditional plant that can treat kinds of illnesses among children, including to prevent them from supernatural things. Kaluppini indigenous people practice and believe in their traditional plants to cure their children. Traditional birth attendants play a crucial role in providing these traditional plants. Information provided in this study could be a rational basis for health-related stakeholders to develop programs of health education and promotion for indigenous communities.

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“…Several systematic reviews of randomized controlled trials (RCTs) were conducted to evaluate the effects of curcumin supplementation on body composition including body weight, body mass index (BMI), and waist circumference [ 19 , 20 , 21 , 22 , 23 ]. Although most reviews included overweight or obese adults, some included participants with normal BMI [ 19 , 21 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

The Effect of Curcumin Supplementation on Anthropometric Measures among Overweight or Obese Adults

Alsharif

Almuhtadi

2021

Nutrients

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Over the past decades, the worldwide prevalence of obesity has dramatically increased, thus posing a serious public health threat. Obesity is associated with the development of comorbid conditions and psychological disorders. Several lifestyle interventions have been proposed to tackle obesity; however, long-term maintenance of these interventions often proves challenging. In addition, among the different types of diets there is still a debate about the optimal macronutrient composition that will achieve the best results in weight loss. Recently, several commonly used spices such as pepper, ginger, and curcumin have been shown to play a beneficial role in obesity management. Therefore, exploring the effects of certain herbs or dietary spices on obesity may be promising. Among these spices, curcumin, which is the primary component of the spice turmeric, has gained great interest for its multiple health benefits. Several randomized controlled trials have investigated the potential favorable effects of curcumin supplementation on anthropometric measures. The aim of this review is to evaluate the effect of curcumin supplementation on the anthropometric indices among overweight or obese adults.

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Does Turmeric/curcumin Supplementation Change Anthropometric Indices in Patients with Non-alcoholic Fatty Liver Disease? A Systematic Review and Meta-analysis of Randomized Controlled Trials

Cited by 21 publications

References 60 publications

Nutritional Approach Targeting Gut Microbiota in NAFLD—To Date

Nutritional Approach Targeting Gut Microbiota in NAFLD—To Date

Traditional Medicine for Children among Kaluppini Indigenous People in South Sulawesi

The Effect of Curcumin Supplementation on Anthropometric Measures among Overweight or Obese Adults

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