2018
DOI: 10.1111/codi.14445
|View full text |Cite
|
Sign up to set email alerts
|

Does transanal local resection increase morbidity for subsequent total mesorectal excision for early rectal cancer?

Abstract: Aim Local excision is recommended for early rectal cancer (pT1). Complementary total mesorectal excision (cTME) is warranted when bad pathological features are present. The impact of a prior local resection on the outcome remains unclear. The aim of this study was to assess if prior local excision increases the morbidity of a subsequent cTME compared with primary TME. Methods From 2001 to 2016 all patients who underwent TME after local excision for rectal adenocarcinoma were studied. All were matched (1:1) wit… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
30
2

Year Published

2019
2019
2022
2022

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 21 publications
(32 citation statements)
references
References 22 publications
0
30
2
Order By: Relevance
“…2). The pooled 30-day mortality rate from all 15 studies 8,11,30,31,[36][37][38][39][41][42][43][44][45][46]49 reporting this outcome was 0.71% and included 425 patients.…”
Section: Thirty-day Mortalitymentioning
confidence: 99%
See 1 more Smart Citation
“…2). The pooled 30-day mortality rate from all 15 studies 8,11,30,31,[36][37][38][39][41][42][43][44][45][46]49 reporting this outcome was 0.71% and included 425 patients.…”
Section: Thirty-day Mortalitymentioning
confidence: 99%
“…Piessen 2012 46 Morino 2013 11 Levic 2013 42 Dulskas 2019 32 Coton 2019 31 Levic 2021 43 Clermonts 2020 30…”
Section: Risk Ratio M-h Random 95% CI Yearmentioning
confidence: 99%
“…Moreover, the quality of the TME resection was not determined at the beginning of the TME era. In most patients, no residual tumor was detected in resected specimens; thus, the actual impact of poor mesorectal quality after a completion TME remains unknown [9]. Prognostically, the more important risk factor was an intraoperative perforation in the rectal wall, which was always documented.…”
Section: Discussionmentioning
confidence: 99%
“…A primary problem with this approach is the risk of intraoperative perforation at the local excision site, which might impact the surgical treatment and the outcome. It remains unclear whether an intraoperative perforation raises the risks of postoperative morbidity [8, 9] or the risk of requiring an APR [10, 11]. In addition, it is not clear whether intraoperative perforations compromise oncological outcomes.…”
Section: Introductionmentioning
confidence: 99%
“…Coton C et al . present a retrospective review on the morbidity following a total mesorectal excision (TME) performed after local excision of a T1 rectal cancer for adverse pathologic features. An increasing number of patients with a T1 mid to low rectal lesion are being offered transanal excision in order to prevent the functional morbidity of a transabdominal TME including low anterior resection syndrome or permanent stoma with an abdominoperineal resection .…”
mentioning
confidence: 99%