Abstract:Tranexamic acid (TXA) has been widely used to reduce blood loss and postoperative transfusion rate in orthopedic surgeries. This study aimed to investigate the safety and effectiveness of TXA in undernourished older adults with hip fracture. A total of 216 patients were classified into undernutrition and normal groups, based on the Geriatric Nutritional Risk Index. Eighty-two patients were randomized to receive intravenous TXA at 15 mg/kg before incision; another 1 g was administered intravenously for 3 h post… Show more
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