Does the type of treatment supporter influence tuberculosis treatment outcomes in Zimbabwe? [Short communication]

Mlilo, N.; Sandy, Charles; Harries, Anthony; Kumar, Ashwini; Masuka, Nyasha; Nyathi, B; Edginton, M. E.; Isaakidis, Petros; Manzi, Marcel; Siziba, N.

doi:10.5588/pha.13.0002

Cited by 6 publications

(5 citation statements)

References 2 publications

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“…Family members have also been reported as the second most preferred (38.36%) type of treatment supporters in another cross-sectional study in Pakistan and a qualitative study in Nigeria noticed maximum emotional and physical support from the members of the family. The community-based treatment provider has been reported as the first choice (71.60%) treatment provider in a mixed-method study in Uganda [8][9][10][11]. The present retrospective study revealed ASHAs as the most preferred treatment supporters by the patients, while family members were their second choice; a similar observation has also been made by Alipanah et al [12].…”

Section: Discussionsupporting

confidence: 85%

“…At present the various DR-TB treatment regimens used for the management of DR-TB cases are (a) shorter oral Bdq-containing MDR/RR-TB regimen: it consists of intensive phase (IP) of [(4-6) Bdq (6), levofloxacin (Lfx), clofazimine (Cfz), Z, E, H-h, ethionamide (Eto)] and continuation phase (CP) of [5 (Lfx, Cfz, Z, E)], total duration is of 9-11 months ; (b) longer oral M/XDR-TB regimen is of 18-20 months with no IP and CP, [18-20 Lfx, Bdq (six months or longer), linezolid (Lzd), Cfz, cycloserine (Cs)]; (c) bedaquiline, pretomanid, and linezolid (BPaL) regimen [ (6)(7)(8)(9) parenchymal damage, on chest radiography), (f) no military TB, TB meningitis, CNS-TB, (g) women who are not pregnant or lactating, (h) no uncontrolled cardiac arrhythmia, (i) QTcF interval less than 500 ms in electrocardiogram (ECG), (j) normal serum electrolytes, and (k) no history of additional risk factors for torsades de pointes. All the above criteria must be met.…”

Section: Introductionmentioning

confidence: 99%

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Impact of Treatment Supporters on the Treatment Outcomes of Drug Resistant-Tuberculosis (DR-TB) Patients: A Retrospective Cohort Study

Giri¹,

Kumar²,

Giri³

et al. 2022

Cureus

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Background: Drug resistant-tuberculosis (DR-TB) patients are provided universal drug susceptibility testing (UDST), anti-TB drugs for the treatment of DR-TB, nutritional support (Nikshay Poshan Yojana -the financial incentive of rupees five hundred per month for each notified DR-TB patient for the duration for which the patient is on anti-TB drugs) by the Government of India.Methods: This retrospective cohort record-based study was conducted in DR-TB patients. Some 1095 DR-TB patients who have initiated treatment at Nodal DR-TB Centre, Darbhanga Medical College and Hospital (DMCH), Darbhanga, and continued their anti-TB drugs at home blocks were followed till their treatment outcome was known. Data were analyzed by statistical experts of DMCH.Results: Treatment supporters comprised 688 (62.83%) females and 407 (37.17%) males. Different types of treatment supporters noted were accredited social health activists (ASHAs) 622 (56.80%), family members 365 (33.33%), and community health workers 108 (09.86%). Treatment outcome as transfer out was observed in 08 (1.29%), 10 (2.74%), and 13 (12.03%) cases among ASHAs, family members, and community health workers, respectively [statistically significant (p < 0.0001)].Conclusion: ASHAs proved to be the best treatment supporters in comparison to both family members and community health workers for multi-drug resistant TB (MDR/RR-TB) patients.

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Section: Discussionsupporting

confidence: 85%

Section: Introductionmentioning

confidence: 99%

Impact of Treatment Supporters on the Treatment Outcomes of Drug Resistant-Tuberculosis (DR-TB) Patients: A Retrospective Cohort Study

Giri¹,

Kumar²,

Giri³

et al. 2022

Cureus

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“…A retrospective study in Thailand found that 90% of patients selected a family member [ 10 ]. Similarly, a cluster-randomized trial in Nepal showed that 89% of patients opted for a family person, while a retrospective cohort study in Zimbabwe found this figure to be 40%, second highest among the four treatment supporter categories [ 11 , 12 ]. A large community randomized trial in South Africa showed that 59% of the TB patients who could choose their treatment supporter would opt for a family member [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Type of Treatment Supporters in Successful Completion of Tuberculosis Treatment: A Retrospective Cohort Study in Pakistan

Hussain

Hasnain

Hussain

et al. 2018

TOIDJ

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Background The World Health Organization has recommended a patient-centered approach to tuberculosis drug administration. A central element of the patient-centered strategy is the use of treatment supporters to evaluate and elevate adherence to the treatment regimen and to address poor adherence when it occurs. This study was led to determine the part of various treatment supporters in the successful completion of treatment. Method This study was conducted in two locales of Sindh, Hyderabad and Mirpurkhas. Information gathered included age, gender, regions, sort of treatment supporters (relatives, community and health facility workers) and treatment outcomes. Results Of the 773 patients incorporated into the study, 86.8% picked a family supporter, 7.63% selected community worker and 5.56% chose health facility worker as their treatment supporter. Women and younger patients were more likely to prefer that family members supervise their treatment. Treatment achievement rates among the patients regulated by the three kinds of treatment supporters, were not altogether unique in relation to each other (p=0.23 Chi square). Conclusion The study demonstrates that TB patients ought to be urged to pick the supporter of their inclination as selection of treatment supporter outside the health system does not adversely affect TB treatment outcomes in limited resource settings.

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“…DOT-TB will improve TB patients' adherence to treatment 14 . The presence of DOT-TB improves healing rate by 72% and reduces the effects of loss of follow-up 15 .…”

Section: Discussionmentioning

confidence: 96%

“…During this time the DOT-TB gain knowledge about TB from health authorities of the TB patient to deliver treatment in the health facilities 19 . This shows the importance of training for family members of DOT-TB on how to provide support for people in DOTS programs 15 .…”

Section: Discussionmentioning

confidence: 99%

The Practice of Home-based Direct Observer Treatment of Patients with Positive Pulmonary Tuberculosis (DOT – TB) at Kebumen District of Indonesia

Pranoto

Claramita

Pramantara

2018

rpcpe

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To cite this article: Pranoto T, Claramita M, Pramantara IDP. The practice of home-based direct observer treatment of patients with positive pulmonary tuberculosis (DOT -TB) at Kebumen district of Indonesia. Rev Prim Care Prac and Educ. 2018; 1(2):ABSTRACT Background: Tuberculosis (TB) is a major global health problem, even though TB can be prevented and treated. The WHO Global Tuberculosis Report 2015 reported 1.5 million deaths from TB, of which 1.1 million were TB with HIV-negative and 0.4 million were HIV-positive tuberculosis. As many as 25% of deaths from TB were in productive ages between 15 to 54 years. Low adherence is a major cause of treatment failure, drop-out and the rising number of cases of MDR (Multi Drugs Resistance). Adherence is also a key to improve the cure rate of treatment of TB patients. Home-based Direct Observer Treatment of patients with positive pulmonary Tuberculosis (DOT-TB) or in Bahasa Indonesia also known as Pengawas Minum Obat (PMO) may improve adherence and increase the TB cure rate and success rate. The DOT-TB has tasks to oversee, remind, motivate and assist TB patients who are undergoing the treatment process. Background of DOT-TB in improving adherence needs to be explored by examining their experiences, which can be expressed by using a phenomenological qualitative study to explore the meaning and significance of their experiences. Objectives: This study aimed to explore the efforts of DOT-TB in performing their duties, the constraints arising from these efforts, benefits, and expectations of the DOT-TB position. Methods: This study applied a qualitative approach with descriptive phenomenological methodology. The number of informants were 21 people divided into groups of DOT-TB whose patients were perfectly recovered (7 people), groups of DOT-TB whose patients were drop-out or failed (7 people) and a group of 7 TB programmers. Each group participated in the Focus Group Discussion (FGD) for 90-120 minutes. Results: The results of the study indicate that the presence of DOT-TB is very important and necessary in the management of TB. The biggest challenge of DOT-TBs in performing their duties are communication barriers due to differences in hierarchy and social status in the society. Their sense of hesitancy was a major challenge of DOT-TB in charge. According to respondents, the ideal DOT-TB is someone close to the patients, has patience, compassion, enough knowledge about TB and good communication skills. Conclusions: In order to perform their duties well, DOT-TBs require training concerning tuberculosis and communication.

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Does the type of treatment supporter influence tuberculosis treatment outcomes in Zimbabwe? [Short communication]

Cited by 6 publications

References 2 publications

Impact of Treatment Supporters on the Treatment Outcomes of Drug Resistant-Tuberculosis (DR-TB) Patients: A Retrospective Cohort Study

Impact of Treatment Supporters on the Treatment Outcomes of Drug Resistant-Tuberculosis (DR-TB) Patients: A Retrospective Cohort Study

Type of Treatment Supporters in Successful Completion of Tuberculosis Treatment: A Retrospective Cohort Study in Pakistan

The Practice of Home-based Direct Observer Treatment of Patients with Positive Pulmonary Tuberculosis (DOT – TB) at Kebumen District of Indonesia

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