Does the Prevalence of Metabolic Syndrome in Pre- and Post-Menopausal Women Differ by the ATP III and IDF Criteria?

Abstract

A AB BS S T TR RA AC CT T O Ob b j je ec c t ti i v ve e: :The aims of this study we re the es ti ma ti on and com pa ri son of car di o vas cular risk fac tors and the pre va len ce of me ta bo lic syndro me (MetS) among pre-me no pa u sal (pre-M) and post-me no pa u sal (post-M) wo men. M Ma a t te e r ri i a al l a an nd d M Me et t h ho od ds s: : This study was con duc ted on 664 (pre-M: 378, post-M: 286) wo men, aged bet we en 30-64 ye ars. Body we ight and wa ist cir cum feren ces (WC) were measured in all par ti ci pants. Ad di ti o nally, body mass in dex (BMI) and wa ist/hip ra ti o (WHR) were cal cu la ted, and li pid pro fi les we re de ter mi ned. R Re e s su ul lt ts s: : The me an ages of pre-M wo men and post-M wo men we re fo und as 42.1 ± 4.50 and 56.2 ± 4.19 ye ars, res pec ti vely (p< 0.001). Me an WC (p< 0.001), WHR (p< 0.001), systo lic ar te ri al pres su re (SAP) (p< 0.001), and di as to lic arte ri al pres su re (DAP) (p< 0.001) le vels we re sig ni fi cantly hig her in post-M wo men as com pa red to pre-M wo men. The me an fas ting plas ma glu co se (FPG) (p= 0.005), low-den sity li pop ro te in cho leste rol (LDL-C) (p= 0.017), trigl yce ri des (TG) (p= 0.017), and to tal cho les te rol/high den sity li pop rote in cho les te rol (TC/HDL-C) (p= 0.043) le vels we re sig ni fi cantly lo wer in pre-M wo men. Ho we ver, TC le vel was sig ni fi cantly hig her in post-M wo men (p< 0.001). We fo und a sig ni fi cant in cre a se in the pre va len ce of the MetS among the post-me no pa u sal wo men de pen ding upon the International Diabetes Federation (IDF) and The National Cholesterol Education Program Adult Treatment Panel III (NCEP AT P I II) cri te ri a. C Co on nc c l lu u s si i o on n: : Me no pa u se is an im por tant risk fac tor for me ta bo lic syndro me. MetS was mo re pre va lent among post me no pa u sal wo men compared to the pre me no pa u sal wo men de pen ding upon both cri te ri a. K Ke ey y W Wo or rd ds s: : Me ta bo lic syndro me X; os te o po ro sis, post me no pa u sal Ö ÖZ ZE ET T A Am ma aç ç: : Bu ça lış ma, pre-me no po zal (pre-M) ve post-me no po zal (post-M) ka dın la rın kar di yovas kü ler risk fak tör le ri ve me ta bo lik sen drom (MetS) sık lı ğı yö nün den in ce len me si ve kar şı laş tı rıl -ma sı ama cıy la plan lan mış tır. G Ge e r re eç ç v ve e Y Yö ön n t te em m l le er r: : Bu ça lış ma yaş la rı 30-64 yaş ara sı de ği şen 664 (pre-M: 378, post-M: 286) ka dın ol gu da ger çek leş ti ril di. Vü cut ağır lı ğı ve bel çev re si (BÇ) bü tün olgu lar da öl çül dü. Ay rı ca beden kit le in dek si (BKİ) ve bel-kal ça ora nı (BKO) he sap lan dı ve li pid profil le ri be lir len di. B Bu ul l g gu u l la ar r: : Pre-M ve post-M ka dın ol gu la rın or ta la ma yaş la rı sı ra sıy la, 42.1 ± 4.50 ve 56.2 ± 4.19 ola rak be lir len di (p< 0.001). Or ta la ma BÇ (p<0.001), BKO (p< 0.001), sis to lik kan basın cı (SKB) (p< 0.001), ve di yas to lik kan ba sın cı (DKB) (p< 0.001) se vi ye le ri post-M ka dın lar da pre-M ka dın la ra gö re an lam lı dü zey de da h...

Menopause and metabolic syndrome in the Middle East countries; a systematic review and meta-analysis study

“…In the primary search, 60 full text articles were related to our topic. After considering inclusion and exclusion criteria, 20 articles were included to qualitative analysis [8,15,[18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35]. In each selected study, the prevalence of MetS was reported according to different criteria; 17 reports based on NCEP ATPIII [8, 15, 18-29, 31, 33-35], 3 reports [22,27,32] based on IDF (2 reports were separately given prevalence data based on NCEP ATPIII and IDF criteria), 2 reports based on World Health Organization (WHO) and the other based on American Heart Association (AHA) [26,30].…”

“…Since, the related studies were found just from two countries of the Middle East region; Iran and Turkey, sub-group analysis was performed based on these countries. Among 17 studies, 11 reports were from Iran [8,15,18,20,21,23,24,27,28,33,34], and others were from Turkey [19,22,25,29,31,35].…”

The incidence of Metabolic Syndrome in Subclinical Hypothyroid patients

“…According to the data of Turkish Adult Adults with Heart Disease and Risk Factors (TEKHARF), the prevalence of MetS in adults 30 years and older was 32.8% (38.6% in women and 27% in men) . Akbulut et al (2011) found that the incidence of MetS was 30.2% in premenopausal women and 47.6% in postmenopausal women according to the NCEP ATP III criteria. Kitiş et al (2010) found the incidence of MetS to be 31.9%.…”

The Importance of Metabolıc Syndrome In Women

“…[25,26] Premenopozal ve postmenopozal dönemdeki kadınlarda kardiyovasküler risk faktörleri ve MetS sıklığının karşılaştırılması amacıyla, 30-64 yaş arası 664 kadın ile yapılan bir çalışmada, postmenopozal kadınlarda MetS daha yüksek oranda saptanmış ve menopozun MetS için önemli bir risk faktörü olduğu sonucuna varılmıştır. [27] Brown et al (2008) tarafından yapılan çalışmada, postmenopozal kadınlarda anjiografi ile KVH tanısı almış 372 kadında, ATP III kriterlerine göre MetS prevalansı %70 bulunmuştur. [28] Diyabet, hipertansiyon ve kilo artışı menopoz sonrası dönemde kadınlarda KVH açısından ciddi birer risk faktörü olarak değerlendirilmelidir.…”