Does the presence of postmenopausal symptoms influence susceptibility to vertebral deformity?

Prevalence of hot flushes and night sweats around the world: a systematic review

“…The literature review recovered 11 relevant papers from European countries [22][23][24][25][26][27][28][29][30][31][32] . In a populationbased, pan-European study of 4023 postmenopausal women ranging in age from 50 to 64 years, the prevalence of hot flushes was 73% and sleep disturbances occurred in 45% 32 .…”

Impact of hot flashes and night sweats on carotid intima–media thickness and bone mineral density among postmenopausal women

“…Previous studies that included older women beyond the menopause transition [12][13][14][15] generally did not find a significant association between vasomotor symptoms and BMD. One such study [12] found that significantly more women with vertebral osteoporosis remembered ever having had vasomotor symptoms at the time of menopause than did women without vertebral osteoporosis.…”

“…One such study [12] found that significantly more women with vertebral osteoporosis remembered ever having had vasomotor symptoms at the time of menopause than did women without vertebral osteoporosis. The studies of older women assessed vasomotor symptoms retrospectively, many years (often decades) after the vasomotor symptoms actually occurred, introducing the potential for inaccurate recall [12][13][14][15]. To avoid this, the group of symptomatic women in the present study included patients with symptoms only; some of the older patients had had vasomotor symptoms for years.…”

Vasomotor symptoms in infertile premenopausal women: a hitherto unappreciated risk for low bone mineral density

“…Of note, and consistent with our findings, these investigators reported a significantly higher prevalence of smokers among women experiencing NS. Similarly, Scoutellas et al (29) were unable to demonstrate an association between recalled symptoms and vertebral fractures in a population-based study of postmenopausal women who were 50-64 years of age. The older age of the enrolled women, the excessive reporting of postmenopausal estrogen therapy use by women acknowledging a history of VMS in the Rancho Bernardo study, and the long period of time elapsed since the occurrence of VMS all may have explained the inconsistencies in findings in the observations noted in these latter studies, when compared with our data.…”