“…The distinguished roles of P53 and KI67 in cancer biology are well-documented, with their overexpression being a harbinger of aggressive disease and poor prognosis across various cancers [ [15] , [16] , [17] , [18] ]. In the context of LSCC, the heightened expression of these proteins, alongside the deregulation of hsa_circ_0069,399 and hsa-miR-2110_R-1, reinforces the potential of circRNAs as biomarkers for disease diagnosis and progression.…”