Does the metabolic syndrome predict mobility impairment in the elderly?

Joint Association of Obesity and Metabolic Syndrome With Incident Mobility Limitation in Older Men and Women--Results From the Health, Aging, and Body Composition Study

“…Obesity, especially abdominal obesity, is also strongly associated with insulin resistance, dyslipidemia, and the metabolic syndrome (MetS) ( 8 ). The MetS is a cluster of cardiovascular risk factors, which is also associated with poorer physical functioning and predicts mobility limitation Composition Study Sari Stenholm , 1 , 2 Annemarie Koster , 3 Dawn E. Alley , 4 Denise K. Houston , 5 Alka Kanaya , 6 Jung Sun Lee , 7 Anne B. Newman , 8 Suzanne Satterfi eld , 9 Eleanor M. Simonsick , 1 Marjolein Visser , 10 , 11 Tamara B. Harris , 3 and Luigi Ferrucci 1 for the Health, Aging, and Body Composition Study ( 9 -13 ). The prevalence of the MetS is higher in obese persons even when the role of high waist circumference is factored out ( 14 ).…”

Risk Factors for Mobility Decline in Community-Dwelling Older Adults: A Systematic Literature Review

“…Sources of bias most commonly related to study attrition, specifically lack of details provided regarding reasons for loss to followup or differences in key characteristics between those included and those lost to follow-up. Nine studies (Avlund et al, 2000;Ayis, Bowling, Gooberman-Hill, & Ebrahim, 2007;Ayis et al, 2006;Eronen et al, 2013;Manty et al, 2009;Onder et al, 2003;Rantakokko et al, 2012;van den Brink et al, 2004;Weiss et al, 2012) (9/58, 16%) were rated as high risk of bias for the study attrition domain, and 33 studies (Abizanda et al, 2013;An & Lu, 2016;Auais et al, 2018Auais et al, , 2019Avlund, Damsgaard, & Osler, 2004;Avlund et al, 2002;Avlund, Lund, et al, 2004;Avlund, Pedersen, & Schroll, 2003;Carbone et al, 2013;Chen et al, 2012;Crimmins & Saito, 1993;Deshpande et al, 2014;Duan-Porter et al, 2019;Eggermont et al, 2014;Fried et al, 2000;Guralnik, Ferrucci, Balfour, Volpato, & Di Iorio, 2001;Koster et al, 2005;LaCroix et al, 1993;Lang et al, 2008;Lee et al, 2005;Leveille et al, 2001Leveille et al, , 2007Lindberg & Tilvis, 1998;Mänty et al, 2007;Nilsson et al, 2008Nilsson et al, , 2010Pine, Gurland, & Chren, 2000Rantakokko et al, 2016;<...>…”

“…(Guralnik et al, 1993(Guralnik et al, , 2001Ho et al, 1997;Schroll et al, 1997) 1.4-3. Avlund et al, 2000;Guralnik et al, 2001;Ho et al, 1997;LaCroix et al, 1993) 0.8-3.6 Very low BMI outside of normal range 14,924 8 (Carbone et al, 2013;Crimmins & Saito, 1993;Deshpande et al, 2014;Guralnik et al, 2001;Ho et al, 1997;LaCroix et al, 1993;Lindberg & Tilvis, 1998;Tsuji et al, 2018) 0.8-2.1 Very low…”