“…This study from Seoul (South Korea) aimed to define the radiological and clinical characteristics of secondary osteosarcoma after retinoblastoma, quantify the clinical survivorship, and understand the value of a radionuclide bone scan in early detection. 2 Between February 2000 and December 2019, the authors treated 540 patients for retinoblastoma. A total of 12 patients (six male, six female) subsequently developed osteosarcoma in the extremities, and two of these patients had two sites of osteosarcoma (ten femurs, four tibiae).…”