Does the Addition of Hyperbaric Oxygen Therapy to the Conventional Treatment Modalities Influence the Outcome of Sudden Deafness?

Abstract

The addition of HBO therapy to the conventional treatment significantly improves the outcome of SD, especially in patients younger than 50 years. Additional HBO therapy provides limited benefit in patients older than 50 years and no benefit in patients older than 60 years.

Hyperbaric Oxygen Therapy for the Treatment of Acute Cochlear Disorders and Tinnitus

“…In addition, 4% no longer suffered from tinnitus, 81.3% observed a decrease in tinnitus intensity and 1.2% a temporary increase in tinnitus intensity, whereas 13.5% revealed their condition to be unchanged [1]. These results were confirmed in current studies [2][3][4][5][6].Recently four studies have been published on the effect of an initial HBO therapy for the treatment of SNHL [7][8][9][10]. Flunkert et al [7] have found that hearing improvement and the effect on tinnitus after initial HBO therapy were similar compared to the effects of infusion therapy with a plasma expander and vasodilator.…”

“…In contrast, Fattori et al [9] concluded that HBO should be considered the preferred treatment, since significantly more patients experienced a significantly greater hearing improvement in the HBO group as compared to the vasodilator-treated group. Aslan et al [10] revealed a significantly greater mean hearing gain (37.9 dB) after combined treatment with HBO, glucocorticoids (prednisone) and betahistine compared to patients who received the drugs without HBO (20 dB). The authors concluded that the addition of HBO to conventional treatment significantly improves the outcome of SNHL, especially in patients younger than 50 years, but not in patients older than 60 years.…”

Clinical Practice Guideline

“…Although costs may vary considerably among facilities, queries by the committee showed that typical Younger patients respond better to hyperbaric oxygen therapy (HBOT) than older patients (the age cutoffs varied from 50-60 years). 173,[235][236][237][238] Early HBOT is better than late HBOT (early is defined from 2 weeks to 3 months). 173,177,235,236,[238][239][240][241] Patients with moderate to severe hearing loss benefit more from HBOT than those with mild hearing loss (moderate hearing loss cutoff was usually at 60 dB).…”

Prieūminio Idiopatinio Neurosensorinio Klausos Pažeidimo Prognostiniai Veiksniai

“…Taip pat pastebima, kad šiandieniniai gydymo metodai tapo invazyvūs, užtikrina medikamento patekimą į vidinę ausį. Manoma, kad vazodilatatoriai, vitaminai, steroidai, antikoaguliantai, histamino preparatai, diuretikai, prostaciklinai, hipervoleminė hemodiliucija, hiperbarinė oksigenacija, kiti gydymo metodai yra efektyvūs ir taikomi praktikoje tiek atskirai, tiek derinant keletą preparatų tarpusavyje [7,13,[17][18][19][20][21][22][23][24][25][26][27][28][29][30][31]. Vis dėlto labai sudėtinga įvertinti įvairių medikamentų terapinį efektyvumą dėl to, kad skirtingų gydymo metodų terapinis efektyvumas prilygsta spontaninio pasveikimo dažniui (32-65%) [2,19,28,31].…”