Does systemic heparin reduces thrombosis rate of radiocephalic fistula: A double-blinded randomized study

Abstract

Background/Objective: The National Kidney Foundation Kidney disease outcomes quality initiative guidelines suggest that the creation of more native arteriovenous fistulas (AVFs) would improve the quality of life of end stage renal failure patients. However, the ability to comply with this suggestion is affected by the failure rate of AVFs mainly due to thrombosis. Heparin is a well-accepted treatment to prevent thrombosis in general but has not been suggested in arteriovenous fistula. This study was conducted to investigate the effect of intraoperative systemic heparin on the thrombosis rate and associated morbidities over a duration of six weeks.

Effect of Systemic Intraoperative Heparin Use on Upper Extremity Arteriovenous Fistula Patency in End-Stage Renal Disease Patients

“…End-stage renal disease (ESRD) is increasing in prevalence worldwide [ 1 ]. ESRD patients require a method of access to allow hemodialysis or peritoneal dialysis [ 2 , 3 ].…”

“…ESRD patients require a method of access to allow hemodialysis or peritoneal dialysis [ 2 , 3 ]. Options include temporary venous lines, intraperitoneal catheters, or formation of the arteriovenous fistula (AVF) [ 1 – 3 ]. AVF is an important method due to its longevity and lower rate of complications [ 1 – 3 ].…”

“…Options include temporary venous lines, intraperitoneal catheters, or formation of the arteriovenous fistula (AVF) [ 1 – 3 ]. AVF is an important method due to its longevity and lower rate of complications [ 1 – 3 ]. This involves the creation of a continuous anastomosis between a suitable artery and vein, typically in the upper limb, to allow development of a suitable access site [ 3 ].…”

“…There are a number of complications associated with AVF formation including bleeding, infection, limb ischaemia, failure to mature, and thrombosis [ 1 , 3 , 4 ]. Thrombosis can develop in the early postoperative phase or can be delayed [ 1 ].…”

Cystic lymphangioma of abdominal wall in an adult: a rare site

“…Other sites are in the maxilla, superior mediastinum, mesentery, retroperitoneal region, pelvis and lower limbs. 2,3 Rarely it occurs on the abdominal wall. There is no predilection for either sex the etiology is unclear, but they are considered due to failure of communication between the primary lymphatic sacs to drain into the venous system.…”