Does serum neutrophil gelatinase-associated lipocalin biomarker detect the early deterioration in renal functions in patients with insulin-dependent diabetes mellitus undergoing coronary artery bypass graft surgery?

Bugra, Onursal

doi:10.5606/tgkdc.dergisi.2014.7780

Cited by 2 publications

(3 citation statements)

References 35 publications

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“…Microalbuminuria is one of the sensitive markers of increased capillary permeability and may be useful to study the systemic inflammatory response after CABG. 6 , 22 , 23 According to previous investigations, urinary microalbuminuria increased significantly in the early postoperative period and one day after CABG.…”

Section: Discussionmentioning

confidence: 90%

Telmisartan decreases microalbuminuria in patients with type 2 diabetes mellitus following coronary artery bypass grafting

Furat

Doğan

İlhan

et al. 2017

CVJA

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SummaryObjective:This prospective study aimed to investigate the effects of the selective angiotensin receptor antagonist, telmisartan, on microalbuminuria after coronary artery bypass surgery in patients with diabetes mellitus.Methods:Patients were divided into two groups with block randomisation, using the sealed envelope technique: group T (telmisartan group) consisted of patients who received the angiotensin receptor blocking agent telmisartan 80 mg daily for at least six months in the pre-operative period; group N-T (non-telmisartan group) consisted of patients who received no telmisartan treatment. Clinical and demographic characteristics, operative and postoperative features, microalbuminuria and high-sensitivity C-reactive protein levels were compared.Results:Forty patients met the eligibility criteria for the study. The groups did not differ with regard to clinical and demographic characteristics, and operative and postoperative features. Microalbuminuria levels between the groups differed significantly in the pre-operative period, first hour postoperatively and fifth day postoperatively. C-reactive protein levels between the groups differed significantly on the fifth day postoperatively.Conclusion:Telmisartan was useful for decreasing systemic inflammation and levels of urinary albumin excretion in patients who had type 2 diabetes mellitus and had undergone coronary artery bypass surgery.

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Section: Discussionmentioning

confidence: 90%

Telmisartan decreases microalbuminuria in patients with type 2 diabetes mellitus following coronary artery bypass grafting

Furat

Doğan

İlhan

et al. 2017

CVJA

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“…[4] Preoperative comorbidities and intraoperative factors are of utmost importance and they may be modifiable factors for developing AKI. [5] Karkouti et al [16] described major risk factors of AKI as follows: intraoperative mean arterial pressure, pre-and intraoperative anemia, need for intraoperative red blood cell transfusion, and pre-and intraoperative proinflammatory activity due to other organic diseases.…”

Section: Discussionmentioning

confidence: 99%

“…[4] Acute kidney injury may occur in a range from minimal elevation in sCr to anuria. Currently, many studies have shown that mild changes in sCr levels can be associated with high morbidity and mortality rates in the early and late postoperative period, and even after discharge from hospital with cardiac and renal recovery.…”

mentioning

confidence: 99%

Mitral and aortic valve surgery-related acute kidney injury: affecting factors and its one year follow-up

İşcan¹

2017

Turk Gogus Kalp Dama

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ÖZAmaç: Bu çalışmada izole kalp kapak cerrahisi sonrası akut böbrek hasarının prevalansı araştırıldı ve risk faktörleri ve bir yıllık takip sonuçları belirlendi.Ça lış ma pla nı: Ocak 2008 -Aralık 2014 tarihleri arasında aort ve mitral kapak cerrahisi yapılan toplam 220 hasta (106 erkek, 114 kadın; ort. yaş 50.6±14.7 yıl; dağılım 14-79 yıl) retrospektif olarak incelendi. Hastaların başlangıç özellikleri, eşlik eden hastalıkları, cerrahi parametreleri ve cerrahi sonrası sonuçları kaydedildi. Hastalar Akut Böbrek Hasarı Ağı Kriterleri kullanılarak cerrahi öncesi ve sonrası kreatinin değerleri ile değerlendirildiği üzere, akut böbrek hasarı olanlar ve olmayanlar olarak iki gruba ayrıldı. Bul gu lar:Tüm hastaların 57'sinde akut böbrek hasarı gelişti. Bu hastaların 12'sinde hemodiyaliz ihtiyacı oldu (evre 1, n=40; evre 2, n=12; evre 3, n=5). Akut böbrek hasarı gelişen hastalar, daha yüksek diabetes mellitus oranı ile daha yaşlı olma eğilimindeydi. Bu hastalarda cerrahi sonrası sepsis, kanama revizyonu, atriyal fibrilasyon ve intraaortik balon pompası ihtiyacı oranları daha yüksek ve yoğun bakım ünitesinde ve hastanede kalış süresi daha uzundu. Akut böbrek hasarı gelişmeyen hastalara kıyasla, gelişen hastalarda, daha fazla eritrosit transfüzyonu gerekli oldu.So nuç: Çalışma sonuçlarımız, Akut Böbrek Hasarı Ağı kriterlerine göre cerrahi sonrası hafif düzeyde kreatinin değişiklikleri ile tanılanan akut böbrek hasarının prognoz açısından önemli bir komplikasyon olduğunu göstermektedir. Yaş, diabetes mellitus ve kan transfüzyonu cerrahi sonrası akut böbrek hasarının başlıca risk faktörleridir. Kalp cerrahisi ile ilişkili akut böbrek hasarının erken ve geç dönem sonuçlarının önlenmesi için hastalar cerrahi öncesinde dikkatlice değerlendirilmelidir.Anah tar söz cük ler: Akut böbrek hasarı; kalp kapak cerrahisi; cerrahi sonrası morbidite. ABSTRACTBackground:This study aims to investigate the prevalence of acute kidney injury after isolated cardiac valve surgery, and to identify risk factors and one-year follow-up results.

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Does serum neutrophil gelatinase-associated lipocalin biomarker detect the early deterioration in renal functions in patients with insulin-dependent diabetes mellitus undergoing coronary artery bypass graft surgery?

Cited by 2 publications

References 35 publications

Telmisartan decreases microalbuminuria in patients with type 2 diabetes mellitus following coronary artery bypass grafting

Telmisartan decreases microalbuminuria in patients with type 2 diabetes mellitus following coronary artery bypass grafting

Mitral and aortic valve surgery-related acute kidney injury: affecting factors and its one year follow-up

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