Does recruitment method make a difference? Effects on protocol retention and treatment outcome in elderly depressed patients

Stack, Jacqueline A.; Paradis, Cynthia F.; Reynolds, Charles F.; Houck, Patricia R.; Frank, Ellen; Anderson, Barbara; Mayo, A.; Miller, Mark D.; Rifai, A. Hind; Perel, James M.; Kupfer, David J.

doi:10.1016/0165-1781(94)02617-r

Cited by 20 publications

(13 citation statements)

References 22 publications

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“…These results appear consistent with Stack et al (1995), however, in that study, the “referred” categorization was restricted to traditional clinical referrals (34). Our study's broader definition also included referrals from general healthcare providers, social service agency professionals, or friends and family.…”

Section: Discussionsupporting

confidence: 77%

Recruitment of African Americans and Asian Americans With Late-Life Depression and Mild Cognitive Impairment

Bistricky

Mackin

Chu³

et al. 2010

The American Journal of Geriatric Psychiatry

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Objective-The purpose of this study was to compare the relative effectiveness of several different strategies for recruiting elderly Asians, African Americans, and Caucasians to participate in mental health research.Participants-A total of 35 African American, 24 Asian American, and 215 Caucasian participants were phone-screened for potential enrollment into a University of California, San Francisco Department of Psychiatry treatment outcome study for older adults (60+ years of age) with major depression and mild cognitive impairment. Design-The methods by which participants were recruited were recorded, coded into composite categories, and statistically analyzed to determine whether certain recruitment strategies were disproportionately effective for recruiting participants from the three racial groups.Results-Fisher's exact test analyses revealed that Asians and African Americans were significantly less likely than Caucasians to be recruited through mental health-based methods, and African Americans were significantly more likely than Caucasians and Asians to be recruited via referrals rather than solicitations. Logistic regression, which controlled for potential confounds, largely supported these findings.Conclusions-Findings suggest that the recruitment of elderly African or Asian Americans into mental health treatment outcome research can be facilitated by a flexible consumer-oriented strategy that integrates multiple recruitment methods. Establishing study credibility through nonmental health media and professional referral sources may be especially effective in engaging the participation of elderly Asian Americans; and cultivating ongoing relationships with key gatekeepers, who can observe benefits to the community, may be particularly effective in recruiting elderly African Americans.

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Section: Discussionsupporting

confidence: 77%

Recruitment of African Americans and Asian Americans With Late-Life Depression and Mild Cognitive Impairment

Bistricky

Mackin

Chu³

et al. 2010

The American Journal of Geriatric Psychiatry

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“…Yet rates of the common cancers in the United States are highest among the elderly, and under-representation of this group may affect the generalizability, and consequently, the usefulness of study results. Older African-Americans are particularly difficult to recruit, and as such, remain greatly under-represented in cancer prevention and control studies (4)(5)(6)(7)(8)(9)(10)(11)(12).…”

Section: Introductionmentioning

confidence: 99%

Recruitment in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial: the First Phase of Recruitment at Henry Ford Health System

Lamerato¹,

Jacobsen²,

Johnson³

2008

Cancer Epidemiology, Biomarkers &Amp; Prevention

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“…Effectiveness trials also use advertising to recruit difficult samples such as in research with co-occurring disorders. The association between recruitment method and sample characteristics has been evaluated in clinical trials of depressed elderly patients (Schlernitzauer et al, 1998; Stack et al, 1995), smokers (Harris et al, 2003; Hoving et al, 2007), and Alzheimer’s disease patients (Andersen et al, 2010) with all but one study (Schlernitzauer et al, 1998) finding significant differences in sample characteristics as a function of recruitment method. The association between recruitment method and treatment outcomes has been less well studied.…”

Section: 0 Introductionmentioning

confidence: 99%

“…The association between recruitment method and treatment outcomes has been less well studied. Two studies evaluated the association between recruitment method and study outcomes in depressed elderly patients with both finding no significant difference in outcomes (Schlernitzauer et al, 1998; Stack et al, 1995). …”

Section: 0 Introductionmentioning

confidence: 99%

The potential impact of recruitment method on sample characteristics and treatment outcomes in a psychosocial trial for women with co-occurring substance use disorder and PTSD

Winhusen

Winstanley

Somoza

et al. 2012

Drug and Alcohol Dependence

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Background Recruitment method can impact the sample composition of a clinical trial and, thus, the generalizability of the results, but the importance of recruitment method in substance use disorder trials has received little attention. The present paper sought to address this research gap by evaluating the association between recruitment method and sample characteristics and treatment outcomes in a substance use disorder trial. Method In a multi-site trial evaluating Seeking Safety (SS), relative to Women’s Health Education (WHE), for women with co-occurring PTSD (either sub-threshold or full PTSD) and substance use disorders, one site assessed the method by which each participant was recruited. Data from this site (n=106), which recruited participants from newspaper advertising and clinic intakes, were analyzed. Results Participants recruited through advertising, relative to those from the clinic, had significantly higher levels of baseline drug use and higher rates of meeting DSM-IV-TR criteria for full PTSD. Results suggest that the effectiveness of SS in decreasing PTSD symptoms was greater for participants recruited through advertising relative to those recruited from the clinic. Conversely, the results revealed a significant treatment effect in the clinic-recruited participants, not seen in the advertising-recruited participants, with SS, relative to WHE, participants being more likely to report past week drug use during the follow-up phase. Conclusion Recruitment method may impact sample composition and treatment effects. Replication of this finding would have important implications for substance use disorder efficacy trials which often utilize advertising to recruit participants.

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Does recruitment method make a difference? Effects on protocol retention and treatment outcome in elderly depressed patients

Cited by 20 publications

References 22 publications

Recruitment of African Americans and Asian Americans With Late-Life Depression and Mild Cognitive Impairment

Recruitment of African Americans and Asian Americans With Late-Life Depression and Mild Cognitive Impairment

Recruitment in the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial: the First Phase of Recruitment at Henry Ford Health System

The potential impact of recruitment method on sample characteristics and treatment outcomes in a psychosocial trial for women with co-occurring substance use disorder and PTSD

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