Does Preoperative Rehabilitation Influence the Quality of Life in Patients Who Are Candidates for Lung Transplant?

Polastri, Massimiliano; Dell’Amore, Andrea; Eden, Allaina; Pehlivan, Esra

doi:10.6002/ect.2022.0039

Cited by 8 publications

(5 citation statements)

References 33 publications

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“…Pre-transplant rehabilitative interventions mainly focus on motor and breathing exercises ( 36 ) and have been integrated into an education program. Lung transplant candidates should be encouraged to attend pre-transplant rehabilitation to preserve and improve their HRQOL ( 37 ).…”

Section: Resultsmentioning

confidence: 99%

A narrative review on the management of patients awaiting lung transplantation in Japan

Suzuki,

Yoshino

2023

J Thorac Dis

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Background and Objective The number of lung transplantations performed in Japan is increasing, and post-transplant outcomes are relatively favorable. A major concern is the extremely long waiting time and the high mortality rate on the waitlist. The management of patients before transplantation is very important and essential for further improvement of outcomes. In this review, we summarize the management of patients awaiting lung transplantation in Japan. Methods A literature search was conducted via PubMed in November 2022 using the following keywords: lung transplantation, waiting, management, recipient, and Japan. Peer-reviewed academic journal articles published in English were also included. Key Content and Findings A growing number of studies have evaluated the management of pre-transplant patients. This includes infection control, vaccination, respiratory disease-specific treatment, malignancy, nutrition, rehabilitation, psychosocial assessment, and health-related quality of life (HRQOL) for patients on the waitlist. Each is important, and various evaluation methods and strategies to improve outcomes have been reported. Conclusions Proper and multifaceted management of pretransplant patients is extremely important to reduce the mortality of candidates for lung transplantation. Integrated management is crucial to the success and survival of lung transplant recipients.

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Section: Resultsmentioning

confidence: 99%

A narrative review on the management of patients awaiting lung transplantation in Japan

Suzuki,

Yoshino

2023

J Thorac Dis

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“…Recipients in need of total assistance at the time of retransplantation are much more likely to experience continuing functional limitations after LRT that require the same assistance [ 22 ]. Although rehabilitative outcomes and quality of life in patients receiving or awaiting LT have gained increasing interest [ 23 , 24 ], there is a paucity of data regarding rehabilitation in patients undergoing LRT. Indeed, we found no published experience describing the rehabilitation of patients who have undergone LRT, and it seems that this topic is unexplored.…”

Section: Expected Outcomes Following Lung Retransplantmentioning

confidence: 99%

Rehabilitative goals for patients undergoing lung retransplantation

Polastri,

Reed

2024

JYMS

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Lung retransplantation (LRT) involves a second or subsequent lung transplant (LT) in a patient whose first transplanted graft has failed. LRT is the only treatment option for irreversible lung allograft failure caused by acute graft failure, chronic lung allograft dysfunction, or postoperative complications of bronchial anastomosis. Prehabilitation (rehabilitation before LT), while patients are on the waiting list, is recognized as an essential component of the therapeutic regimen and should be offered throughout the waiting period from the moment of listing until transplantation. LRT is particularly fraught with challenges, and prehabilitation to reduce frailty is one of the few opportunities to address modifiable risk factors (such as functional and motor impairments) in a patient population in which there is clearly room to improve outcomes. Although rehabilitative outcomes and quality of life in patients receiving or awaiting LT have gained increased interest, there is a paucity of data on rehabilitation in patients undergoing LRT. Frailty is one of the few modifiable risk factors of retransplantation that is potentially preventable. As such, it is imperative that professionals involved in the field of retransplantation conduct research specifically exploring rehabilitative techniques and outcomes of value for patients receiving LRT, because this area remains unexplored.

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“…For example, kidney transplant candidates may have different handgrip strength averages than lung transplant candidates, making uniform thresholds impractical. The differences in the averages of certain domains of frailty among transplant candidates displayed in Table 1 highlight the need for organ-specific thresholds [8,[22][23][24][25][26][27][28][29][30][31][32][33][34][35][36].…”

Section: Organ-specific Considerations In Frailty Assessmentmentioning

confidence: 99%

“…Kidney [18,21--25,29,31,32] Liver [8,30,31] Lung [26,27,31] Heart [28,31] Individual www.co-transplantation.com across different organs. Ultimately, adopting this unified approach would enable the implementation of center-level strategies across all solid-organ transplant programs, aimed at improving outcomes for transplant patients.…”

Section: Instrumentmentioning

confidence: 99%

The Liver Frailty Index: a model for establishing organ-specific frailty metrics across all solid organ transplantation

Jutras,

Lai

2024

Current Opinion in Organ Transplantation

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Purpose of review In this review, we discuss the development of the Liver Frailty Index (LFI) and how it may serve as a model for developing other organ-specific frailty indices. Recent findings As the demand for solid organ transplants continues to increase, the transplantation community is enhancing its strategies for organ allocation to gain deeper insights into patient risk profiles and anticipated outcomes. Frailty has emerged as a critical concept in transplant care, offering valuable insights into adverse health outcomes. Standardizing frailty assessment across transplant programs could enhance prognostic accuracy and inform pretransplant interventions. The LFI comprises of three performance-based tests that each represents essential components of the multidimensional frailty construct. This composite metric provides insights beyond liver function and considers nonhepatic comorbid factors. Identifying common frailty principles among all transplant candidates and adopting the LFI methodology, which assesses fundamental frailty principles using liver-specific tools, could establish a foundational pool of shared core frailty principles. From this pool, organ-specific frailty indices could be derived, each equipped with the clinically relevant organ-specific tools to evaluate common core principles. Summary Creating a standardized framework across all solid-organ transplants, with common principles and organ-specific measurements, would facilitate consistent frailty assessment, standardize the integration of the frailty construct into transplant decision-making, and enable center-level interventions to improve outcomes for patients with end-stage organ disease.

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Does Preoperative Rehabilitation Influence the Quality of Life in Patients Who Are Candidates for Lung Transplant?

Cited by 8 publications

References 33 publications

A narrative review on the management of patients awaiting lung transplantation in Japan

A narrative review on the management of patients awaiting lung transplantation in Japan

Rehabilitative goals for patients undergoing lung retransplantation

The Liver Frailty Index: a model for establishing organ-specific frailty metrics across all solid organ transplantation

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